Jungang Xie

TL;DR: The epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of patients with laboratory-confirmed 2019-nCoV infection in Wuhan, China, were reported.

TL;DR: High-flow nasal oxygen may be effective for treating coronavirus disease 2019 patients with mild to moderate acute hypoxemic respiratory failure, however, high- flow nasal oxygen failure was associated with a poor prognosis.

TL;DR: Cell factorial design analysis showed that Hg+Pb+Cd had a interaction on cell viability after 48 or 72 hours of combined exposure, and the results of ultrastructure showed that mitochondria decreased, ridges and matrixes gradually dissolved in rat hippocampal neurons of 5×MM group; nuclear chromatin aggregated was dissolved and the mitochondria also decreased in rat hippocampusal neuron of 10×MMgroup.

TL;DR: Lower plasma CC10 was associated with enhanced airway hyperresponsiveness, and Type 2 inflammation, and Plasma CC10 is potentially useful in predicting T2-high and T1-low asthma.

TL;DR: The hypothesis that Myotubularin-related protein 14 participates in the pathogenesis of COPD is supported and improving mitochondrial function and mitophagy homeostasis may be one of the mechanisms by which MTMR14 alleviates COPD and may potentially be a novel therapeutic target for COPD.