L
Li Zhang
Researcher at Beijing Institute of Genomics
Publications - 16
Citations - 58566
Li Zhang is an academic researcher from Beijing Institute of Genomics. The author has contributed to research in topics: Deep sequencing & Gene. The author has an hindex of 9, co-authored 14 publications receiving 43306 citations. Previous affiliations of Li Zhang include Wuhan Jinyintan Hospital & Chinese Academy of Sciences.
Papers
More filters
Journal ArticleDOI
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang,Yeming Wang,Xingwang Li,Lili Ren,Jianping Zhao,Yi Hu,Li Zhang,Guohui Fan,Jiuyang Xu,Xiaoying Gu,Zhenshun Cheng,Ting Yu,Jia'an Xia,Yuan Wei,Wenjuan Wu,Xuelei Xie,Wen Yin,Li Hui,Min Liu,Yan Xiao,Hong Gao,Li Guo,Jungang Xie,Guang-Fa Wang,Rongmeng Jiang,Zhancheng Gao,Qi Jin,Jianwei Wang,Bin Cao +28 more
TL;DR: The epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of patients with laboratory-confirmed 2019-nCoV infection in Wuhan, China, were reported.
Journal ArticleDOI
Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
Nanshan Chen,Min Zhou,Xuan Dong,Jie-Ming Qu,Fengyun Gong,Yang Han,Yang Qiu,Jingli Wang,Ying Liu,Yuan Wei,Jia'an Xia,Ting Yu,Xinxin Zhang,Li Zhang +13 more
TL;DR: Characteristics of patients who died were in line with the MuLBSTA score, an early warning model for predicting mortality in viral pneumonia, and further investigation is needed to explore the applicability of the Mu LBSTA scores in predicting the risk of mortality in 2019-nCoV infection.
Journal ArticleDOI
A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19.
Bin Cao,Yeming Wang,Danning Wen,Wen Liu,Jingli Wang,Guohui Fan,Lianguo Ruan,Bin Song,Yanping Cai,Ming Wei,Xingwang Li,Jia'an Xia,Nanshan Chen,Jie Xiang,Ting Yu,Tao Bai,Xuelei Xie,Li Zhang,Caihong Li,Ye Yuan,Hua Chen,Huadong Li,Hanping Huang,Shengjing Tu,Fengyun Gong,Ying Liu,Yuan Wei,Chongya Dong,Fei Zhou,Xiaoying Gu,Jiuyang Xu,Zhibo Liu,Yi Zhang,Li Hui,Lianhan Shang,Ke Wang,Kunxia Li,Xia Zhou,Xuan Dong,Zhaohui Qu,Sixia Lu,Xujuan Hu,Shunan Ruan,Shanshan Luo,Jing Wu,Lu Peng,Fang Cheng,Lihong Pan,Jun Zou,Chunmin Jia,Juan Wang,Xia Liu,Shuzhen Wang,Xudong Wu,Qin Ge,Jing He,Haiyan Zhan,Fang Qiu,Li Guo,Chaolin Huang,Thomas Jaki,Frederick G. Hayden,Peter Horby,Dingyu Zhang,Chen Wang +64 more
TL;DR: In hospitalized adult patients with severe Covid-19, no benefit was observed with lopinavir–ritonavir treatment beyond standard care, and future trials in patients withsevere illness may help to confirm or exclude the possibility of a treatment benefit.
Journal ArticleDOI
Heightened Innate Immune Responses in the Respiratory Tract of COVID-19 Patients.
Zhuo Zhou,Zhuo Zhou,Lili Ren,Li Zhang,Jiaxin Zhong,Jiaxin Zhong,Yan Xiao,Jia Zhilong,Li Guo,Jing Yang,Jing Yang,Chun Wang,Chun Wang,Shuai Jiang,Donghong Yang,Guoliang Zhang,Hongru Li,Fuhui Chen,Yu Xu,Mingwei Chen,Zhancheng Gao,Jian Yang,Jie Dong,Bo Liu,Xiannian Zhang,Weidong Wang,Kunlun He,Qi Jin,Mingkun Li,Mingkun Li,Mingkun Li,Jianwei Wang +31 more
TL;DR: The expression of proinflammatory genes, especially chemokines, was markedly elevated in COVID-19 cases compared to community-acquired pneumonia patients and healthy controls, suggesting that SARS-CoV-2 infection causes hypercytokinemia.
Journal ArticleDOI
Genomic Diversity of Severe Acute Respiratory Syndrome-Coronavirus 2 in Patients With Coronavirus Disease 2019.
Zijie Shen,Zijie Shen,Yan Xiao,Lu Kang,Lu Kang,Wentai Ma,Wentai Ma,Leisheng Shi,Leisheng Shi,Li Zhang,Zhuo Zhou,Jing Yang,Jing Yang,Jiaxin Zhong,Jiaxin Zhong,Donghong Yang,Li Guo,Guoliang Zhang,Hongru Li,Yu Xu,Mingwei Chen,Zhancheng Gao,Jianwei Wang,Lili Ren,Mingkun Li,Mingkun Li +25 more
TL;DR: SARS-CoV-2 evolves in vivo after infection, which may affect its virulence, infectivity, and transmissibility, and it is necessary to strengthen the surveillance of the viral evolution in the population and associated clinical changes.