J
Junyang Qian
Researcher at Stanford University
Publications - 22
Citations - 895
Junyang Qian is an academic researcher from Stanford University. The author has contributed to research in topics: Lasso (statistics) & Biobank. The author has an hindex of 10, co-authored 20 publications receiving 392 citations. Previous affiliations of Junyang Qian include Peking University.
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Journal ArticleDOI
Genetics of 35 blood and urine biomarkers in the UK Biobank
Nasa Sinnott-Armstrong,Nasa Sinnott-Armstrong,Nasa Sinnott-Armstrong,Yosuke Tanigawa,David Amar,David Amar,Nina Mars,Christian Benner,Matthew Aguirre,Guhan Venkataraman,Michael Wainberg,Hanna Ollila,Hanna Ollila,Hanna Ollila,Tuomo Kiiskinen,Tuomo Kiiskinen,Aki S. Havulinna,Aki S. Havulinna,James P. Pirruccello,James P. Pirruccello,Junyang Qian,Anna Shcherbina,Anna Shcherbina,FinnGen,Fatima Rodriguez,Themistocles L. Assimes,Themistocles L. Assimes,Vineeta Agarwala,Robert Tibshirani,Trevor Hastie,Samuli Ripatti,Samuli Ripatti,Jonathan K. Pritchard,Mark J. Daly,Mark J. Daly,Mark J. Daly,Manuel A. Rivas +36 more
TL;DR: In this article, the genetic basis of 35 blood and urine laboratory measurements in the UK Biobank (n = 363,228 individuals) was evaluated and the results delineate the genetic underlying of biomarkers and their causal influences on diseases and improve genetic risk stratification for common diseases.
Posted ContentDOI
Genetics of 38 blood and urine biomarkers in the UK Biobank
Nasa Sinnott-Armstrong,Yosuke Tanigawa,David Amar,Nina Mars,Matthew Aguirre,Guhan Venkataraman,Michael Wainberg,Hanna Ollila,Hanna Ollila,Hanna Ollila,James P. Pirruccello,James P. Pirruccello,Junyang Qian,Anna Shcherbina,Fatima Rodriguez,Themistocles L. Assimes,Themistocles L. Assimes,Vineeta Agarwala,Robert Tibshirani,Trevor Hastie,Samuli Ripatti,Samuli Ripatti,Jonathan K. Pritchard,Jonathan K. Pritchard,Mark J. Daly,Mark J. Daly,Mark J. Daly,Manuel A. Rivas,Finn Gen +28 more
TL;DR: The genetic basis of 38 blood and urine laboratory tests is evaluated, which tissues contribute to the biomarker function, the causal influences of the biomarkers, and how this can be used to predict disease are shown.
Journal ArticleDOI
Some methods for heterogeneous treatment effect estimation in high dimensions
Scott Powers,Junyang Qian,Kenneth Jung,Alejandro Schuler,Nigam H. Shah,Trevor Hastie,Robert Tibshirani +6 more
TL;DR: This work proposes and analyzes 3 methods for estimating heterogeneous treatment effects using observational data, and presents results of applying the 2 most promising methods to data from The SPRINT Data Analysis Challenge, from a large randomized trial of a treatment for high blood pressure.
Journal ArticleDOI
A fast and scalable framework for large-scale and ultrahigh-dimensional sparse regression with application to the UK Biobank
Junyang Qian,Yosuke Tanigawa,Wenfei Du,Matthew Aguirre,Christopher C. Chang,Robert Tibshirani,Manuel A. Rivas,Trevor Hastie +7 more
TL;DR: A computational framework called batch screening iterative lasso (BASIL) that can take advantage of any existing lasso solver and easily build a scalable solution for very large data, including those that are larger than the memory size is proposed.
Journal ArticleDOI
Significant sparse polygenic risk scores across 813 traits in UK Biobank
Yosuke Tanigawa,Junyang Qian,Guhan Venkataraman,Johanne Marie Justesen,Ruilin Li,Robert Tibshirani,Trevor Hastie,Manuel A. Rivas +7 more
TL;DR: The sparse PRS model trained on European individuals showed limited transferability when evaluated on non-European individuals in the UK Biobank.