Laboratory for Advanced Materials and New Catalysis, School of Chemistry and Materials Science, Hubei University, Wuhan 430062, China,Laboratory of Natural Gas Utilization and Applied Catalysis, Dalian Institute of Chemical Physics of Chinese Academy of Sciences, Dalian 116023,China, and Jingmen Technological College, Jingmen 448000, ChinaReceived June 30, 2004

Advances in Homogeneous and Heterogeneous Catalytic Asymmetric Epoxidation

An Efficient Asymmetric Epoxidation Method for trans-Olefins Mediated by a Fructose-Derived Ketone

Chemical and biological synthesis of chiral epoxides

The highly stereoselective oxidation of polyunsaturated fatty acids by cytochrome P450BM-3

γ-Amino acids have attracted considerable attention as biologically active compounds in the central nervous system (CNS) of mammals. Over the last few years, significant interest in the stereoselective synthesis and practical application of linear and cyclic chiral γ-amino acids in the synthesis and design of α,β- and β,γ-hybrid peptides with definite secondary structures and design of nanotubes has been reported, thus demonstrating the theoretical interest and the practical importance of γ-amino acids. An overview of synthetic approaches to linear and cyclic chiral γ-amino acids and derivatives is presented. Data on the practical applications of γ-amino acids are also discussed.

Stereoselective synthesis of γ-amino acids

Epoxydation d'alcene-3ols-1 par le systeme Ti(O-iPr) 4 , tortrate de diethyle et hydroperoxyde de t-butyle: obtention d'oxirannepropanols. L'oxirannepropanol est oxyde en acide oxiranneacetique puis traite par NH 4 OH pour obtenir l'acide (−)-amino-4 hydroxy-3 butyrique

K. B. Sharpless

Papers

Asymmetric epoxidation of homoallylic alcohols. Synthesis of (-)-γ-amino-β(R)-hydroxybutyric acid (GABOB)