Journal ArticleDOI
Asymmetric epoxidation of homoallylic alcohols. Synthesis of (-)-γ-amino-β(R)-hydroxybutyric acid (GABOB)
B. E. Rossiter,K. B. Sharpless +1 more
TLDR
In this article, the system of Ti(O-iPr) 4, tortrate de diethyle et hydroperoxyde de t-butyle: obtention d'oxirannepropanol est oxyde en acide oxiranneacetique.Abstract:
Epoxydation d'alcene-3ols-1 par le systeme Ti(O-iPr) 4 , tortrate de diethyle et hydroperoxyde de t-butyle: obtention d'oxirannepropanols. L'oxirannepropanol est oxyde en acide oxiranneacetique puis traite par NH 4 OH pour obtenir l'acide (−)-amino-4 hydroxy-3 butyriqueread more
Citations
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Journal ArticleDOI
Advances in Homogeneous and Heterogeneous Catalytic Asymmetric Epoxidation
TL;DR: This paper presents results of aalysis experiment conducted at the Dalian Institute of Chemical Physics of Chinese Academy of Sciences (Dalian 116023) and Jingmen Technological College (Jingmen 448000) using gas chromatography for the recovery of Na6(CO3) from Na2SO4.
Journal ArticleDOI
An Efficient Asymmetric Epoxidation Method for trans-Olefins Mediated by a Fructose-Derived Ketone
Yong Tu,Zhi-Xian Wang,Yian Shi +2 more
Journal ArticleDOI
Chemical and biological synthesis of chiral epoxides
Pascale Besse,Henri Veschambre +1 more
TL;DR: The chiral epoxidation of olefins with per&d8 and monooxygenases with cytochromes P-450 shows good chiral recognition ability, and the chiral reagents used in this synthesis show low levels of chiral specificity.
Journal ArticleDOI
The highly stereoselective oxidation of polyunsaturated fatty acids by cytochrome P450BM-3
Jorge H. Capdevila,Shozou Wei,Christian F. Helvig,John R. Falck,Yuri Belosludtsev,Gilles Truan,Sandra E. Graham-Lorence,Julian A. Peterson +7 more
TL;DR: The formation by P450BM-3 of a single oxidant species capable of olefinic bond epoxidation and sp3 carbon hydroxylation is proposed, demonstrating that product chemistry and catalytic outcome are critically dependent on active site spatial coordinates responsible for substrate binding and productive orientation between heme-bound active oxygen and acceptor carbon bond(s).
Journal ArticleDOI
Stereoselective synthesis of γ-amino acids
Mario Ordóñez,Carlos Cativiela +1 more
TL;DR: An overview of synthetic approaches to linear and cyclic chiral γ-amino acids and derivatives is presented in this article, where data on the practical applications of these acids are also discussed.
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