K
K. Indira Priyadarsini
Researcher at Bhabha Atomic Research Centre
Publications - 83
Citations - 4665
K. Indira Priyadarsini is an academic researcher from Bhabha Atomic Research Centre. The author has contributed to research in topics: Radical & Radiolysis. The author has an hindex of 29, co-authored 82 publications receiving 4145 citations. Previous affiliations of K. Indira Priyadarsini include University of Mumbai & Homi Bhabha National Institute.
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Journal ArticleDOI
Role of phenolic O-H and methylene hydrogen on the free radical reactions and antioxidant activity of curcumin.
K. Indira Priyadarsini,Dilip K. Maity,G. H. Naik,M. Sudheer Kumar,Mazhuvancherry Kesavan Unnikrishnan,J. G. Satav,Hari Mohan +6 more
TL;DR: To understand the relative importance of phenolic O-H and the CH-H hydrogen on the antioxidant activity and the free radical reactions of Curcumin, biochemical, physicochemical, and density functional theory studies were carried out and it is definitely concluded that the phenolic OH plays a major role in the activity of curcumin.
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Photophysics, photochemistry and photobiology of curcumin : Studies from organic solutions, bio-mimetics and living cells
TL;DR: The intracellular curcumin showed more fluorescence in tumor cells than in normal cells and fluorescence spectroscopy could be used to monitor its preferential localization in the membrane of tumor cells and the possibility of developingCurcumin, as a bimolecular sensitive fluorescent probe is discussed.
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Free radical studies of ellagic acid, a natural phenolic antioxidant.
TL;DR: Ellagic acid, a plant-derived polyphenol, inhibits gamma-radiation (hydroxyl radical) induced lipid peroxidation in rat liver microsomes in a dose- and concentration-dependent manner and has been found to be a good scavenger of peroxynitrite.
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Transport of liposomal and albumin loaded curcumin to living cells: an absorption and fluorescence spectroscopic study.
TL;DR: It was found that liposomal vehicle is capable of loading more curcumin in to cells than HSA or aqueous-DMSO, and lymphoma cells show preferential uptake ofCurcumin to lymphocytes.
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Effect of Solvent on the Excited-state Photophysical Properties of Curcumin¶
TL;DR: Steady-state absorption and fluorescence characteristics of curcumin have been found to be sensitive to the solvent characteristics and the nuclear magnetic resonance study in CDCl3 and dimethyl sulfoxide-D6 supports the fact that the enol form is present in the solution by more than about 95% in these solvents.