A
Amit Kunwar
Researcher at Bhabha Atomic Research Centre
Publications - 102
Citations - 2905
Amit Kunwar is an academic researcher from Bhabha Atomic Research Centre. The author has contributed to research in topics: Chemistry & Curcumin. The author has an hindex of 25, co-authored 90 publications receiving 2407 citations. Previous affiliations of Amit Kunwar include Homi Bhabha National Institute & Indian Institute of Chemical Technology.
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Journal ArticleDOI
Quantitative cellular uptake, localization and cytotoxicity of curcumin in normal and tumor cells
TL;DR: Cytotoxicity studies in different cell lines indicated that the toxicity of curcumin increased with increasing uptake, and sub-cellular fractionation of curCumin-loaded MCF7 cells supported the differential distribution ofCurcumin in membrane, cytoplasm and nuclear compartments of cell with maximum localization in the membrane.
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Transport of liposomal and albumin loaded curcumin to living cells: an absorption and fluorescence spectroscopic study.
TL;DR: It was found that liposomal vehicle is capable of loading more curcumin in to cells than HSA or aqueous-DMSO, and lymphoma cells show preferential uptake ofCurcumin to lymphocytes.
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Concentration dependent antioxidant/pro-oxidant activity of curcumin studies from AAPH induced hemolysis of RBCs.
TL;DR: It is concluded that curcumin exhibits both antioxidant/pro-oxidant activity, in a concentration dependent manner.
Journal Article
Free radicals, oxidative stress and importance of antioxidants in human health -
Amit Kunwar,K.I. Priyadarsini +1 more
TL;DR: It is necessary to validate the utility of antioxidants in improvement of human health in order to take full advantage of their therapeutic potential.
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Comparative study of copper(II)-curcumin complexes as superoxide dismutase mimics and free radical scavengers.
Atanu Barik,B. Mishra,Amit Kunwar,Ramakant Mahadeo Kadam,Liang Shen,Sabari Dutta,Subhash Padhye,Ashis K. Satpati,Hong-Yu Zhang,K. Indira Priyadarsini +9 more
TL;DR: Two stoichiometrically different copper(II) complexes of curcumin, were examined for their superoxide dismutase (SOD) activity, free radical-scavenging ability and antioxidant potential and one-electron oxidation of the two complexes by radiolytically generated azide radicals produced phenoxyl radicals, indicating that the phenolic moiety ofCurcumin in the complexes participates in free radical reactions.