K
Kahuku Oades
Researcher at Beckman Coulter
Publications - 7
Citations - 83
Kahuku Oades is an academic researcher from Beckman Coulter. The author has contributed to research in topics: Cancer & Nucleic acid methods. The author has an hindex of 2, co-authored 7 publications receiving 80 citations.
Papers
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Journal ArticleDOI
Diagnosis of the Small Round Blue Cell Tumors Using Multiplex Polymerase Chain Reaction
Qing-Rong Chen,Qing-Rong Chen,Gordon Vansant,Kahuku Oades,Maria Pickering,Jun S. Wei,Young K. Song,Joseph Monforte,Javed Khan +8 more
TL;DR: The results suggest that this molecular test based on a multiplex PCR reaction may assist the physician in the rapid confirmation of the diagnosis of the diagnoses of these cancers.
Patent
Compositions and methods for the analysis of degraded nucleic acids
TL;DR: In this article, the authors proposed methods for determining the quality of nucleic acids (e.g., the degree of degradation) in a nucleic acid sample, and also provided methods for producing a gene expression profile from a degraded RNA sample.
Proceedings ArticleDOI
Abstract 3664: Breast cancer companion diagnostic platform based on objectively defined tumor co-expression patterns stratifies multiple clinical and therapeutic endpoints comparison to existing molecular subtyping definitions
Daniel R. Rhodes,Scott A. Tomlins,Dafydd G. Thomas,Paul Williams,Peter Wyngaard,Seth Sadis,Kahuku Oades,Lien Vo,S. Chattopadhyay,Yipeng Wang,Byung-In Lee,Joseph Monforte +11 more
TL;DR: It is demonstrated that breast cancer modules can be used to recapitulate the molecular subtypes of breast cancer and to have prognostic and predictive properties similar to the current multigene tests.
Proceedings ArticleDOI
Abstract 3665: An EMT gene expression diagnostic predicts resistance to EGFR and MEK-targeted therapies in cell lines and patients
Sean Eddy,Paul Williams,Mark Tomilo,Seth Sadis,Peter Wyngaard,Lien Vo,Kahuku Oades,Hyun-Soo Kim,Yipeng Wang,Byung-In Lee,Joseph Monforte,Daniel R. Rhodes +11 more
TL;DR: The EMT signature was significantly associated with a major tumor co-expression pattern representing mesenchymal and/or stromal phenotype observed in almost all major solid tumor types, and predicted resistance to cetuximab.
Journal ArticleDOI
NGS-based targeted RNA sequencing for expression analysis of patients with triple-negative breast cancer using a modulized, 96-gene biomarker panel.
TL;DR: Development of targeted RNA-sequencing methodology which combines the power of a universal RNA amplification with NGS for an ultra-deep expression analysis of multiple target genes, enabling <100 ng of sample input for multi-gene analysis in a single tube format is described.