Kai-Ren Zhao

TL;DR: Wang et al. as mentioned in this paper reported a novel Cas12a-based electrochemiluminescence biosensor for target amplification-free human papilloma virus subtype (HPV-16) DNA detection.

TL;DR: A simple enzyme-free target-triggered catalytic hairpin assembly (CHA) circuit was adopted to synthesize a tripedal DNA walker, which showed high selectivity and excellent reproducibility, demonstrating its practical application in bioanalysis.

TL;DR: In this paper, gold@carbon dots nanoalloys (Au@CDs) were synthesized by directly heating carbon dots and HAuCl4 aqueous solution to boiling.

TL;DR: In this paper, an amplified electrochemiluminescence (ECL) ratiometric biosensor for p53 DNA sequence assay was described based on gold@carbon dots nanoflowers (Au@CDs), gold@luminol nanoparticles as luminophors and an enzyme-free DNA walker for signal amplification.

TL;DR: Using this strategy, HIV and HPV-16 DNAs are successfully quantitatively detection with detection limits of 30 fM and 0.32 pM (S/N = 3), respectively, and this system does not rely on multiplex signal reporting molecules, thus simplifying the detection system and avoiding the likelihood of cross interferences presented in the assay.