K
Kai Wang
Researcher at Tongji University
Publications - 81
Citations - 2165
Kai Wang is an academic researcher from Tongji University. The author has contributed to research in topics: Angiogenesis & Placenta. The author has an hindex of 23, co-authored 72 publications receiving 1502 citations. Previous affiliations of Kai Wang include Dalian Medical University & University of California, San Diego.
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Journal ArticleDOI
Exosomes Released from Tumor-Associated Macrophages Transfer miRNAs That Induce a Treg/Th17 Cell Imbalance in Epithelial Ovarian Cancer.
Jieru Zhou,Xiaoduan Li,Xiaoli Wu,Ting Zhang,Qinyi Zhu,Xinjing Wang,H. W. Wang,Kai Wang,Yingying Lin,Xipeng Wang +9 more
TL;DR: Results indicate that exosomes mediate the interaction between TAMs and T cells, generating an immune-suppressive microenvironment that facilitates EOC progression and metastasis, and suggest that targeting these exosome or their associated miRNAs might pave the way for the development of novel treatments for EOC.
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Exosomes From Women With Preeclampsia Induced Vascular Dysfunction by Delivering sFlt (Soluble Fms-Like Tyrosine Kinase)-1 and sEng (Soluble Endoglin) to Endothelial Cells.
TL;DR: It is proposed that exosomes mediated efficient transfer of sFlt-1 and sEng to endothelial cells to damage vascular functions and induce complications in preeclampsia patients.
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Isolation and Characterization of Cancer Stem Cells from High-Grade Serous Ovarian Carcinomas
Qizhi He,Xun-Zhen Luo,Kai Wang,Qian Zhou,Hong Ao,Yan Yang,Shu-Xia Li,Ying Li,Hui-Ting Zhu,Tony Duan +9 more
TL;DR: Results revealed that HGSCs are created and propagated by a small number of undifferentiated tumorigenic cells, and therapeutic targeting of these cells could be beneficial for treatment of HG SCs.
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Expression of aryl hydrocarbon receptor in human placentas and fetal tissues.
TL;DR: Examination of AhR protein expression in human placentas from normal and severe preeclamptic pregnancies, as well as human fetal tissues from the second trimester of pregnancy, suggests that the AhR plays a critical role in syncytiotrophoblasts of human Placentas and epithelium of many fetal organs.
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An endogenous aryl hydrocarbon receptor ligand inhibits proliferation and migration of human ovarian cancer cells
Kai Wang,Kai Wang,Yan Li,Yi-Zhou Jiang,Cai-Feng Dai,Cai-Feng Dai,Manish S. Patankar,Jiasheng Song,Jing Zheng,Jing Zheng +9 more
TL;DR: It is found that AhR was widely present in many histotypes of ovarian cancer tissues, and the ITE might potentially be used for therapeutic intervention for at least a subset of human ovarian cancer.