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Kaiu Prikk

Researcher at Tallinn University of Technology

Publications -  6
Citations -  224

Kaiu Prikk is an academic researcher from Tallinn University of Technology. The author has contributed to research in topics: COPD & Translational medicine. The author has an hindex of 5, co-authored 6 publications receiving 183 citations.

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Journal ArticleDOI

Direct demonstration of tissue uptake of an inhaled drug: proof-of-principle study using matrix-assisted laser desorption ionization mass spectrometry imaging.

TL;DR: This is the first reported study in applying MALDI-MSI to demonstrate the localization of a drug administered at therapeutic levels, and it is demonstrated that ipratropium is rapidly absorbed into the airway wall.
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Lung dysfunction of chronic smokers with no signs of COPD.

TL;DR: It is concluded that lung function deviation and lung structural changes are present in CSs before the clinical signs of airway obstruction reveal, and body plethysmography and diffusing capacity measurement with routine spirometry can provide valuable information for detection of changes reflecting to the early onset of COPD.
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Understanding drug uptake and binding within targeted disease micro-environments in patients: a new tool for translational medicine.

TL;DR: It is demonstrated that robust imaging data could be generated confirming drug localization in pulmonary regions of COPD patients with tumor pathology, and bridging comprehension that forms a knowledge base that can be used by society to develop a better treatment and medicine for patients.
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Mucin5B expression by lung alveolar macrophages is increased in long-term smokers.

TL;DR: M UC5B is expressed in a subset of lung AMs and long‐term cigarette smoking may increase the level of MUC5B produced by these cells.