Kalevi Pyörälä

TL;DR: The proportion of peripheral (toe, leg) amputations was markedly higher in diabetic patients who also tended to have more reamputations during the follow-up than did nondiabetic subjects, and the diabetic status per se was a statistically significant risk factor for mortality in women, but not in men.

TL;DR: Evidence is provided that NIDDM, its metabolic control, and the duration of diabetes are important predictors of stroke in elderly subjects, particularly in women, and fasting insulin level appears to be a risk factor for stroke in Elderly nondiabetic subjects.

TL;DR: It is suggested that microalbuminuria may be a feature of the prediabetic state and that the increase in albumin excretion rate may be related to increases in glucose and insulin concentrations.

TL;DR: In addition to reducing mortality and morbidity in coronary heart disease patients, simvastatin markedly reduces use of hospital services, thus offsetting most of its cost.

TL;DR: The excess coronary heart disease mortality and morbidity rates among persons with low SES are considerable in Finland and to bring the mortality rates of low- and middle-SES groups down to the level of that of the high- SES group constitutes a major public health challenge.