Karl Kudyba

TL;DR: It is proposed that EcR signaling modulates the effects of EGFR signaling by promoting an undifferentiated state in early stage cyst cells.

TL;DR: MG-LAMP is a sensitive and specific assay that may be useful for the detection of malaria parasites in remote healthcare settings and the findings suggest that it is possible to implement simple molecular tests in facilities with limited resources.

TL;DR: It is shown that repeated mating reduced the sperm pool and increased the percentage of GSCs in M- and S-phase of the cell cycle, and Germline expression of RNA-Interference constructs against G-proteins, or a dominant negative G-protein eliminated the increase in GSC division frequency in mated males.

TL;DR: The current MG-LAMP assay was limited in its ability to detect mixed infection when compared to the PET-PCR, but otherwise proved to be a powerful tool for malaria parasite detection in the field and opens new perspectives in the implementation of surveillance studies in malaria elimination campaigns.

TL;DR: It is shown that a demand for sperm, caused by repeated male mating, increased germline stem cell (GSC) division frequency and the production of gametes in non-mated males, making the highly conserved Serotonin receptors key players in the mechanism regulating tissue replenishment.