Katherine Marsden

TL;DR: The influence of apixaban and rivaroxaban on haemostasis testing extends beyond routine coagulation assays to encompass a plethora of specialisedAssays, including factor assays, lupus inhibitor, and FVIII inhibitor estimation.

TL;DR: In the hands of patients the CoaguChek XS showed good correlation with laboratory determination of INR and compared well with expanded and narrow clinical agreement criteria.

TL;DR: These findings explain the high rate of errors associated with VWD diagnosis and show different VWF assays and activity/antigen ratios show different utility in VWD and type identification.

TL;DR: Findings of haemostasis laboratory tests for one of the DOACs, dabigatran (Pradaxa), tested across a wide range of laboratory assays showed good reproducibility and concordance with expected drug levels assessed by mass spectrometry and were effective to quantify drug levels.

TL;DR: It appears that HSC collections can remain adequate for safe transplantation after up to 14 years of cryostorage, and some precautions may be warranted, namely harvesting higher than normal numbers of HSCs in collections intended for long-term storage and repeating in vitro assays on harvests after long- term storage prior to transplantation.