K
Katrien Fransen
Researcher at Institute of Tropical Medicine Antwerp
Publications - 140
Citations - 6276
Katrien Fransen is an academic researcher from Institute of Tropical Medicine Antwerp. The author has contributed to research in topics: Viral load & Population. The author has an hindex of 38, co-authored 140 publications receiving 5876 citations.
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Journal ArticleDOI
Preexposure Prophylaxis for HIV Infection among African Women
Lut Van Damme,Amy Corneli,Khatija Ahmed,Johan Lombaard,Saidi Kapiga,Mookho Malahleha,Rachel Manongi,Jacob Onyango,Lucky Temu,Modie Constance Monedi,Mankalimeng Makanda,Lisa Saylor,Haddie Kiernan,Stella Kirkendale,Christina Wong,Robert M. Grant,Angela D. M. Kashuba,Kavita Nanda,Justin Mandala,Katrien Fransen,Jennifer Deese,Tania Crucitti,Timothy D Mastro,Douglas Taylor +23 more
TL;DR: Prophylaxis with TDF-FTC did not significantly reduce the rate of HIV infection and was associated with increased rates of side effects, as compared with placebo, and drug adherence appeared to be low.
Journal ArticleDOI
Evaluation of Convalescent Plasma for Ebola Virus Disease in Guinea.
J. van Griensven,Tansy Edwards,X de Lamballerie,Malcolm G Semple,P Gallian,Sylvain Baize,Peter Horby,Hervé Raoul,N’Faly Magassouba,Annick Antierens,C Lomas,Oumar Faye,Amadou A. Sall,Katrien Fransen,Jozefien Buyze,Raffaella Ravinetto,Raffaella Ravinetto,Pierre Tiberghien,Yves Claeys,M De Crop,Lutgarde Lynen,Elhadj Ibrahima Bah,Pete Smith,Alexandre Delamou,A. De Weggheleire,Nyankoye Haba +25 more
TL;DR: The transfusion of up to 500 ml of convalescent plasma with unknown levels of neutralizing antibodies in 84 patients with confirmed EVD was not associated with a significant improvement in survival, and no serious adverse reactions associated with the use of convalscent plasma were observed.
Journal ArticleDOI
Phylogenetic analysis of gag genes from 70 international HIV-1 isolates provides evidence for multiple genotypes.
Joost Louwagie,Francine E. McCutchan,Martine Peeters,Terrence P. Brennan,Eric Sanders-Buell,Gerald A. Eddy,Guido van der Groen,Katrien Fransen,G. M. Gershy-Damet,Robert Deleys,Donald S. Burke +10 more
TL;DR: The genetic variation among HIV-1 isolates is more extensive than previously appreciated and at least seven distinct HIV- 1 genotypes can be identified.
Journal ArticleDOI
Genotypic subtypes of HIV-1 in Cameroon.
J. N. Nkengasong,Wouter Janssens,Leo Heyndrickx,Katrien Fransen,Ndumbe Pm,J. Motte,A. Leonaers,M. Ngolle,Ayuk J,Peter Piot +9 more
TL;DR: Findings on a limited number of viruses suggest extensive env gene diversity of HIV-1 strains from Cameroon, and could have implications for vaccine development in Africa.
Journal ArticleDOI
Laboratory evaluation of four HIV/syphilis rapid diagnostic tests
Annelies Van Den Heuvel,Hilde Smet,Irena Prat,Anita Sands,Willy Urassa,Katrien Fransen,Tania Crucitti +6 more
TL;DR: Although these results suggest that the tests could further improve in accuracy in detection of treponemal antibodies, their introduction into screening programmes to increase the accessibility of HIV/Syphilis diagnosis and treatment for difficult to reach populations in the world is promising.