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Kaustubha A. Prabhune
Researcher at University of Louisville
Publications - 6
Citations - 147
Kaustubha A. Prabhune is an academic researcher from University of Louisville. The author has contributed to research in topics: Transplantation & Internal medicine. The author has an hindex of 4, co-authored 4 publications receiving 141 citations.
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Journal ArticleDOI
Mixed allogeneic chimerism and tolerance to composite tissue allografts.
Kaustubha A. Prabhune,Vijay S. Gorantla,Claudio Maldonado,Gustavo Perez-Abadia,John H. Barker,Suzanne T. Ildstad +5 more
TL;DR: Mixed chimerism‐based tolerance protocols are reviewed, highlighting some unique characteristics (high antigenicity and the presence of active bone marrow) that make CTAs different from solid organ allografts.
Journal ArticleDOI
Composite tissue allotransplantation in chimeric hosts: Part I. Prevention of graft-versus-host disease
Vijay S. Gorantla,Kaustubha A. Prabhune,Gustavo Perez-Abadia,Suzanne T. Ildstad,Claudio Maldonado,Haldun Orhun,Ramsey K. Majzoub,Cedric G. Francois,Thanos P. Kakoulidis,Pascal C. R. Brouha,Gary L. Anderson,Diane J. Pidwell,Warren C. Breidenbach,John H. Barker +13 more
TL;DR: These data demonstrate that established chimeras could be susceptible to GVHD caused by immunocompetent donor cells transferred with the hind limb, and inactivating these cells with irradiation prevents GV HD and destabilization of chimerism, and permits rejection-free graft acceptance.
Journal ArticleDOI
Composite tissue allotransplantation in chimeric hosts part II. A clinically relevant protocol to induce tolerance in a rat model.
Kaustubha A. Prabhune,Vijay S. Gorantla,Gustavo Perez-Abadia,Cedric G. Francois,Marieke Vossen,Luis A. Laurentin-Perez,Warren C. Breidenbach,Gordon G. Wang,Gary L. Anderson,Diane J. Pidwell,John H. Barker,Claudio Maldonado +11 more
TL;DR: It is demonstrated that infusion of donor bone marrow cells into conditioned hosts immediately after limb transplantation results in stable mixed chimerism, robust tolerance, and reliable limb allograft survival.
Journal ArticleDOI
Composite tissue allograft (CTA): tolerance induction without graft vs host disease (GvHD)
Vijay S. Gorantla,Gustavo Perez-Abadia,Kaustubha A. Prabhune,Haldun Orhun,Thanos P. Kakoulidis,Ramsey K. Majzoub,Claudio Maldonado,Gary L. Anderson,Lynn Ogden,Warren C. Breidenbach,Suzanne T. Ildstad,John H. Barker +11 more
TL;DR: This research presents a novel and scalable approach called “Cellular Therapeutics-based Supranational Gastroenterology,” which aims to provide real-time information about the response of the immune system to certain types of wounds.
Journal ArticleDOI
POSA34 Comparative Efficacy and Safety of Treatment Regimens for Advanced, Recurrent, or Metastatic Endometrial Cancer: A Systematic Review
S.P. Yeddala,Nandini U. Yadav,Kaustubha A. Prabhune,John Doucette,C. Harris,I.B. Murimi-Worstell +5 more
TL;DR: In this paper , a comprehensive search strategy was developed to identify relevant articles in PubMed, Embase, and Cochrane from inception to 28 January 2021, a total of 6533 studies were identified and 5029 studies were retained after duplication.