Kazuhiko Uchiyama

TL;DR: Akkermansia muciniphila is introduced as a next-generation beneficial microbe that affects glucose metabolism, lipid metabolism, and intestinal immunity, and that certain food ingredients such as polyphenols may increase the abundance of Akkermansian bacteria in the gut.

TL;DR: Administration of astaxanthin might be a novel approach for the prevention of diabetes nephropathy because it reduced the oxidative stress on the kidneys and prevented renal cell damage.

TL;DR: This study used microarray technology to identify miRNA induced in the colonic mucosa of patients with active ulcerative colitis and confirmed the relationship between intestinal inflammation and miRNA expression remains unclear.

TL;DR: Results indicate that astaxanthin can exert beneficial effects in diabetes, with preservation of β-cell function, and suggests that anti-oxidants may be potentially useful for reducing glucose toxicity.

TL;DR: Results suggest that i) the JAK2/STAT1 pathway is involved in the anticancer agent-mediated PD-L1 transcription; and ii) the anticancer agents altered the tumor immune response which may induce tumor immune escape.