Yuji Naito

TL;DR: Clinical and experimental data suggest dysbiosis may play a pivotal role in the pathogenesis of IBD, and the therapeutic options for manipulating the altered gut microbiota, such as probiotics and fecal microbiota transplantation are reviewed.

TL;DR: Biodegradable conduits or patches seeded with autologous bone marrow cells showed normal function and the tissue-engineering approach may provide an important alternative to the use of prosthetic materials in the field of pediatric cardiovascular surgery.

TL;DR: Ag nanoparticles were found to be very stable, showed sufficient preservation efficacy against mixed bacteria and mixed fungi, and did not penetrate normal human skin, suggesting that Ag nanoparticles may have potential for use as a preservative in cosmetics.

TL;DR: It is suggested that active oxygen species and lipid peroxidation play an important part in the pathogenesis of gastric mucosal injury induced by indomethacin, and that the decreased glutathione peroxidase activity aggravated the injury due to accelerated accumulation of hydrogen peroxide and lipidperoxides in the gastricucosal cell.

TL;DR: The present current evidence indicates that HO-1 induction mediated by multiple pathways can drive the phenotypic shift to M2 macrophages and suggests that HO -1 induction in macrophage is a potential therapeutic approach to immunomodulation in widely diverse human diseases.