K
Kazuhiro Moriyama
Researcher at Fujita Health University
Publications - 23
Citations - 288
Kazuhiro Moriyama is an academic researcher from Fujita Health University. The author has contributed to research in topics: Sepsis & Membrane. The author has an hindex of 6, co-authored 22 publications receiving 190 citations.
Papers
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Journal ArticleDOI
In vitro evaluation of high mobility group box 1 protein removal with various membranes for continuous hemofiltration.
Miho Yumoto,Osamu Nishida,Kazuhiro Moriyama,Yasuyo Shimomura,Tomoyuki Nakamura,Naohide Kuriyama,Yoshitaka Hara,Shingo Yamada +7 more
TL;DR: It is concluded that continuous hemofiltration using the AN69ST membrane is a promising approach for HMGB1‐related sepsis.
Book ChapterDOI
AN69: Evolution of the world's first high permeability membrane.
TL;DR: Since its creation in the early 1970s the AN69 membrane has evolved to meet the requirements and challenges of dialysis therapy, and the basic characteristics of high permeability to fluid and to a wide range of relevant uremic retention products combined with excellent biocompatibility have remained the hallmark of the membrane.
Journal ArticleDOI
Targeting Cytokines, Pathogen-Associated Molecular Patterns, and Damage-Associated Molecular Patterns in Sepsis via Blood Purification.
Kazuhiro Moriyama,Osamu Nishida +1 more
TL;DR: In this review, recent advances in knowledge regarding the role of lipopolysaccharides, cytokines, DAMPs, and neutrophils in the pathogenesis of sepsis are summarized and the potential of blood purification, especially the adsorption technology, for removing immune cells and molecular mediators, thereby serving as a therapeutic strategy againstsepsis is discussed.
Book ChapterDOI
Sustained high-efficiency daily diafiltration using a mediator-adsorbing membrane (SHEDD-fA) in the treatment of patients with severe sepsis.
Osamu Nishida,Tomoyuki Nakamura,Naohide Kuriyama,Yoshitaka Hara,Miho Yumoto,Yasuyo Shimomura,Kazuhiro Moriyama +6 more
TL;DR: The effectiveness of SHEDD-fA, which makes the best use of three principles: dialysis, filtration and adsorption, for mediator removal in the treatment of severe sepsis is described.
Journal ArticleDOI
Involvement of ionic interactions in cytokine adsorption of polyethyleneimine-coated polyacrylonitrile and polymethyl methacrylate membranes in vitro
Kazuhiro Moriyama,Yu Kato,Daisuke Hasegawa,Yasuyoshi Kurimoto,Takahiro Kawaji,Tomoyuki Nakamura,Naohide Kuriyama,Yasuyo Shimomura,Osamu Nishida +8 more
TL;DR: Results indicated that Ionic interactions play a role in cytokine adsorption by the AN69ST membrane but not the PMMA membrane and highlight the clinical relevance of this finding, as well as the potential practical applications for further hemofilter design.