Kazuyuki Sogawa

TL;DR: Although for some pathogens, preanalytical processes should be refined, and the current database should be improved to obtain more accurate results, the MALDI–TOF MS based method performs, in general, as well as conventional methods and is a promising technology in clinical laboratories.

TL;DR: Comparison of protein profiles of the consecutive serum samples obtained during abstinence from a total of 16 chronic alcoholic patients hospitalized for a rehabilitation program generated two peaks that had been downregulated on admission and significantly increased after a one‐week abstinence that may be promising biomarkers for excessive alcohol drinking.

TL;DR: Pre- and postoperative serum protein profiling obtained from pancreatic cancer patients who had curative pancreatectomy using surface-enhanced laser desorption ionization time-of-flight mass spectrometry suggest that ApoC-1 contributes to the aggressiveness of Pancreatic cancer and will be useful as a new therapeutic target.

TL;DR: The findings suggest that serum IL- 12 is a biomarker of the disease activity in POEMS syndrome, and the overproduction of IL-12, as well as VEGF, is likely to play an important role in the pathogenesis of the disorder.

TL;DR: A case of bacterial meningitis caused by Klebsiella pneumoniae is described in which MALDI-TOF MS provided a rapid bacteriological diagnosis, thus enabling early and appropriate treatment.