Sonoko Misawa

TL;DR: Modelling the excitability changes in this group supported the hypothesis that axonal potassium conductances are reduced, resulting in increased supernormality despite membrane depolarization in ALS, and suggest a changing pattern of abnormal membrane properties with disease progression.

TL;DR: Common autoantibodies, antecedent infections, and MRI and neurophysiological results found in this large study offer conclusive evidence that Bickerstaff's brainstem encephalitis and Fisher syndrome form a continuous spectrum with variable CNS and PNS involvement.

TL;DR: Muscle US is a practical and efficient tool to detect fasciculations, particularly in the tongue, and a combination of US and EMG substantially increases the diagnostic sensitivity of ALS.

TL;DR: Before development of typical systemic manifestations, POEMS neuropathy can be distinguished from CIDP by the clinical profile and patterns of nerve conduction abnormalities.

TL;DR: Prominent muscle atrophy in APB and FDI, with relatively preserved ADM appears to be specific to ALS, and presumably reflects part of the pathophysiology and supports the diagnosis of ALS.