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Showing papers by "Keith A. Cengel published in 2001"

Journal Article•DOI•
CD45 Negatively Regulates Monocytic Cell Differentiation by Inhibiting Phorbol 12-Myristate 13-Acetate-dependent Activation and Tyrosine Phosphorylation of Protein Kinase Cδ

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Eric L. Deszo, Danett K. Brake, Keith A. Cengel, Keith W. Kelley, Gregory G. Freund1 •
University of Illinois at Urbana–Champaign1
30 Mar 2001-Journal of Biological Chemistry
TL;DR: CD45 negatively regulates monocyte differentiation by inhibiting phorbol 12-myristate 13-acetate (PMA)-dependent activation of protein kinase C (PKC) δ by impeding PMA-dependent PKCδ tyrosine phosphorylation, suggesting that CD45 is a critical regulator of monocytic cell development.

47 citations