K
Keith A. Jolley
Researcher at University of Oxford
Publications - 173
Citations - 15150
Keith A. Jolley is an academic researcher from University of Oxford. The author has contributed to research in topics: Multilocus sequence typing & Population. The author has an hindex of 54, co-authored 160 publications receiving 12585 citations. Previous affiliations of Keith A. Jolley include Southampton General Hospital & University of Bath.
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BIGSdb: Scalable analysis of bacterial genome variation at the population level
TL;DR: The Bacterial Isolate Genome Sequence Database (BIGSDB) represents a freely available resource that will assist the broader community in the elucidation of the structure and function of bacteria by means of a population genomics approach.
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Open-access bacterial population genomics: BIGSdb software, the PubMLST.org website and their applications.
TL;DR: Developments in the BIGSdb software made from publication to June 2018 are described and it is shown how the platform realises microbial population genomics for a wide range of applications.
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Multilocus Sequence Typing System for the Endosymbiont Wolbachia pipientis
Laura Baldo,Julie C. Dunning Hotopp,Keith A. Jolley,Seth R. Bordenstein,Sarah A. Biber,Rhitoban Ray Choudhury,Cheryl Y. Hayashi,Martin C. J. Maiden,Hervé Tettelin,John H. Werren +9 more
TL;DR: A multilocus sequence typing (MLST) scheme as a universal genotyping tool for Wolbachia was developed and was shown to be effective for detecting diversity among strains within a single host species, as well as for identifying closely related strains found in different arthropod hosts.
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MLST revisited: the gene-by-gene approach to bacterial genomics
Martin C. J. Maiden,Melissa J. Jansen van Rensburg,James E. Bray,Sarah G. Earle,Suzanne A. Ford,Keith A. Jolley,Noel D. McCarthy +6 more
TL;DR: This work draws on the successes of MLST and 16S rRNA gene sequencing to propose a hierarchical gene-by-gene approach that reflects functional and evolutionary relationships and catalogues bacteria 'from domain to strain'.
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Sequence type analysis and recombinational tests (START)
TL;DR: The 32-bit Windows application START performs analyses to aid in the investigation of bacterial population structure using multilocus sequence data and performs analyses including data summary, lineage assignment, and tests for recombination and selection.