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Kenji Takada

Researcher at Osaka University

Publications -  176
Citations -  5062

Kenji Takada is an academic researcher from Osaka University. The author has contributed to research in topics: Masticatory force & Malocclusion. The author has an hindex of 32, co-authored 173 publications receiving 4641 citations. Previous affiliations of Kenji Takada include National University of Singapore.

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Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog

TL;DR: Investigation of the involvement of Runx3 in chondrocyte differentiation by generating Runx2-and-Runx3-deficient (Runx2(-/-)3(-/-)) mice found that chondrospermia differentiation was inhibited depending on the dosages of Run x2 and Runx4, and Run x3- deficient mice showed a complete absence of chond rocyte maturation.
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Skeletal Malformations Caused by Overexpression of Cbfa1 or Its Dominant Negative Form in Chondrocytes

TL;DR: Data show that temporally and spatially regulated expression of Cbfa1 in chondrocytes is required for skeletogenesis, including formation of joints, permanent cartilages, and endochondral bones.
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Core-binding factor beta interacts with Runx2 and is required for skeletal development.

TL;DR: Electrophoretic mobility shift assays and reporter assays showed that Cbfβ was necessary for the efficient DNA binding of Runx2 and for Runx 2-dependent transcriptional activation, which indicates that CBFβ is required for the function of RunX2 in skeletal development.
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Facial Asymmetry in Subjects with Skeletal Class III Deformity

TL;DR: In this paper, the frequency, site, amount, and direction of facial asymmetry in human adults with mandibular prognathism were investigated and the characteristics were associated postnatally with cardinal clinical signs that may indicate a predisposition to facial asymmetric.
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Changes in dentofacial morphology in skeletal Class III children treated by a modified maxillary protraction headgear and a chin cup: a longitudinal cephalometric appraisal.

TL;DR: The results suggest possible orthopaedic effects of the MPH on dentofacial morphology in young females when it is applied before or during acceleration of the pubertal growth spurt.