K
Kenneth W. Liechty
Researcher at University of Colorado Denver
Publications - 157
Citations - 7750
Kenneth W. Liechty is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Wound healing & Medicine. The author has an hindex of 43, co-authored 140 publications receiving 6756 citations. Previous affiliations of Kenneth W. Liechty include Sanford-Burnham Institute for Medical Research & University of Mississippi.
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Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep
Kenneth W. Liechty,Tippi C. MacKenzie,Aimen F. Shaaban,Antoneta Radu,Annemarie Moseley,Robert J. Deans,Daniel R. Marshak,Alan W. Flake +7 more
TL;DR: The data support the possibility of the transplantability of mesenchymal stem cells and their potential utility in tissue engineering, and cellular and gene therapy applications, and seem to have unique immunologic characteristics that allow persistence in a xenogeneic environment.
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Cystic adenomatoid malformation volume ratio predicts outcome in prenatally diagnosed cystic adenomatoid malformation of the lung
Timothy M. Crombleholme,Beverly G. Coleman,Holly L. Hedrick,Kenneth W. Liechty,Lori J. Howell,Alan W. Flake,Mark P. Johnson,N. Scott Adzick +7 more
TL;DR: The authors report the results of prospective use of the CVR both to track tumor growth and regression during gestation and confirm its predictive value in fetuses with CAM, suggesting its usefulness as a predictor of outcome in CAM.
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IL-10 Overexpression Decreases Inflammatory Mediators and Promotes Regenerative Healing in an Adult Model of Scar Formation
William H. Peranteau,Liping Zhang,Nidal Muvarak,Andrea T. Badillo,Antoneta Radu,Philip W. Zoltick,Kenneth W. Liechty +6 more
TL;DR: It is concluded that lentivirus-mediated overexpression of IL-10 decreases the inflammatory response to injury, creating an environment conducive for regenerative adult wound healing.
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Diminished interleukin 6 (IL-6) production during scarless human fetal wound repair.
TL;DR: Diminished production of inflammatory cytokines such as IL-6 may be responsible for the lack of inflammation seen during fetal wound healing and may provide a permissive environment for scarless wound healing.
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Fetal wound repair results in scar formation in interleukin-10-deficient mice in a syngeneic murine model of scarless fetal wound repair.
TL;DR: Wounds in normal fetal skin grafts showed minimal inflammation and normal dermal reticular collagen pattern at the site of the wound, consistent with scarless repair, while wounds in IL-10 knockout fetal skin transplants showed significant inflammation and scar formation.