Kenzo Hirao

TL;DR: Findings indicate a novel mechanism of myocardial dysfunction induced by oxidative stress, and found that promyelocytic leukemia protein and acetylated p53, key proteins involved in stress‐induced premature senescence in proliferating cells, were associated with cellular alterations of senescences in DOX‐treated cardiomyocytes.

TL;DR: FDG-PET/CT is useful for detection of active inflammation not only in patients with active TA before treatment but also in relapsing patients receiving immunosuppressive agents.

TL;DR: Delta EEG power showed negative correlations with LF and LF/HF, suggesting that sympathetic nervous activities continuously fluctuate in accordance with sleep deepening and lightening.

TL;DR: Three-dimensional (3D) mapping systems that have been developed since the 1990 s have contributed to the clarification of the mechanisms of these complex arrhythmias and the improvement of the outcome of ablation procedures.

TL;DR: The safety profile of TCZ was consistent over time regarding mortality, serious infections, malignancy, gastrointestinal perforation, and serious cardiac dysfunction, and these data confirm the longterm safety ofTCZ use in patients with RA in a real-world clinical setting.