K
Khalid S Al Numair
Researcher at King Saud University
Publications - 7
Citations - 456
Khalid S Al Numair is an academic researcher from King Saud University. The author has contributed to research in topics: Glutathione peroxidase & 1,2-Dimethylhydrazine. The author has an hindex of 6, co-authored 7 publications receiving 380 citations.
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Chemopreventive potential of β-Sitosterol in experimental colon cancer model - an In vitro and In vivo study
Albert A Baskar,Albert A Baskar,Savarimuthu Ignacimuthu,Gabriel M. Paulraj,Khalid S Al Numair +4 more
TL;DR: β-sitosterol had chemopreventive potential by virtue of its radical quenching ability in vitro, with minimal toxicity to normal cells, and also attenuated β-catenin and PCNA expression, making it a potential anticancer drug for colon carcinogenesis.
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β-sitosterol prevents lipid peroxidation and improves antioxidant status and histoarchitecture in rats with 1,2-dimethylhydrazine-induced colon cancer.
Arul Albert Baskar,Khalid S Al Numair,Micheal Gabriel Paulraj,Mohammed A. Alsaif,May Al Muamar,Savarimuthu Ignacimuthu +5 more
TL;DR: β-sitosterol by virtue of its antioxidant potential may be used as an effective agent to reduce DMH-induced oxidative stress in Wistar rats and may be an effective chemopreventive drug for colon carcinogenesis.
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Cancer Chemopreventive Potential of Luteolin-7-O-Glucoside Isolated From Ophiorrhiza mungos Linn
TL;DR: LUT7G induced apoptosis by scavenging ROS and suppressing the expression of β-catenin in COLO 320 DM cells and effectively inhibited ACF development in DMH-induced experimental carcinogenesis, suggesting LUT7g can be a potent anticancer drug for colon carcinogenesis.
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In vitro antioxidant and antiproliferative potential of medicinal plants used in traditional Indian medicine to treat cancer.
TL;DR: The results of the present study support the need of further studies to isolate potential anticancer drug with cancer cell-specific cytotoxicity and support the anticancer property of medicinal plants used in the traditional Indian medicine system.
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Protective effect of morin on cardiac mitochondrial function during isoproterenol-induced myocardial infarction in male Wistar rats.
TL;DR: Pre-treatment with morin favorably restored the biochemical and functional parameters to near normal indicating morin to be a significant protective effect on cardiac mitochondrial function against ISO-induced MI in rats.