Ki Churl Chang

TL;DR: It is concluded that HO-1-derived CO reduces HMGB1 release in L PS-activated cells and LPS- or CLP-induced animal model of sepsis.

TL;DR: Taken together, ANT from black soybean seed coat have anti-diabetic effects that are due, in part, to the regulation of glucose transporter 4 and prevention of insulin resistance and pancreatic apoptosis, suggesting a possible use as a drug to regulate diabetes.

TL;DR: The effect of metformin on the expression of pro‐inflammatory cytokines including high mobility group box 1 (HMGB1) in lipopolysaccharide (LPS)‐treated animals and cells is investigated.

TL;DR: The present findings indicate that .O2- may be responsible, at least in part, for the impaired endothelial integrity, enhanced alpha adrenergic receptor-mediated PI turnover and augmented contractility, possibly through modification of calcium channels in STZ-induced short-term diabetic rat aorta.

TL;DR: It is demonstrated that 13-methyl- and 13-ethylberberine alkaloids can be useful as an immunotherapeutic compound for induction of IL-12, which is potentially applicable for tumors, infectious disease, and airway inflammation.