Koichi Hirata

TL;DR: The data obtained here should provide useful information on the molecular mechanism underlying clinical responses to EGFR-TKIs, aid the development of novel therapies for lung cancer, and potentially identify predictive molecular markers for sensitivity to ZD1839.

TL;DR: A 63-year-old man who was asymptomatic underwent a routine medical examination, which revealed a tumor in the pelvic space, and a giant peritoneal loose body was found, made up of thick layers of fibrous tissue with a few cellular components, and necrotic fat tissue in the central position.

TL;DR: The results indicate that ST 6GALNAC1 has a role in the maintenance of CR-CSCs/CICs by activating the Akt pathway in cooperation with galectin-3 and that ST6GalNac1 (or STn antigen) might be a reasonable molecule for CSC/C IC-targeting therapy.

TL;DR: Freshly harvested middle ear effusions were collected from children with otitis media with effusion and compared with transportability of the MEE on mucus-depleted frog palates to show there is a sharp increase in transport with increase in G′ up to 20 dyne/cm2, and at the higher value of G′there is a slow decrease in Transport with increasing G′.

TL;DR: A novel link between expression of ERO1-α and secretion of VEGF is established, providing new evidence for the effectiveness of E RO1- α-targeted therapy in patients with ERO 1-α-expressed cancer.