K
Koji Y. Arai
Researcher at Tokyo University of Agriculture and Technology
Publications - 54
Citations - 924
Koji Y. Arai is an academic researcher from Tokyo University of Agriculture and Technology. The author has contributed to research in topics: Luteinizing hormone & Ovulation. The author has an hindex of 18, co-authored 54 publications receiving 854 citations. Previous affiliations of Koji Y. Arai include University of Kansas & University of Tokushima.
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Journal ArticleDOI
Adverse effects of environmental toxicants, octylphenol and bisphenol A, on male reproductive functions in pubertal rats.
TL;DR: It is demonstrated that OP and BPA can reduce sperm counts resulting from lowered plasma testosterone in male rats just after puberty, raising the possibility of a link between these chemicals and prostate diseases because IGF-I has been implicated in the pathogenesis of human prostate cancers.
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Novel factors in regulation of activin signaling
Kunihiro Tsuchida,Masashi Nakatani,Takashi Matsuzaki,Norio Yamakawa,Zhong Hui Liu,Zhong Hui Liu,YongLi Bao,Koji Y. Arai,Koji Y. Arai,Tatsuya Murakami,Yuka Takehara,Akira Kurisaki,Hiromu Sugino +12 more
TL;DR: Data indicate that ARIP2 is a novel factor regulating cell surface ActRII expression and activin function, and that follistatin and FLRG likely play distinct roles as activin/GDF binding proteins in vivo.
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Expression of Nerve Growth Factor and Its Receptors NTRK1 and TNFRSF1B Is Regulated by Estrogen and Progesterone in the Uteri of Golden Hamsters
Zhanquan Shi,Zhanquan Shi,Koji Y. Arai,Wanzhu Jin,Wanzhu Jin,Qiang Weng,Gen Watanabe,Gen Watanabe,Akira K. Suzuki,Kazuyoshi Taya,Kazuyoshi Taya +10 more
TL;DR: Results suggest that NGF may play important roles in action of steroids on uterine function and changes in uterine weights induced by estradiol-17β and/or progesterone showed the same profile with that of NGF, suggesting that a proliferative act of N GF may be involved in uterusine growth.
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A New Alternative Method for Superovulation Using Passive Immunization Against Inhibin in Adult Rats
Harumichi Ishigame,Mohamed S. Medan,Mohamed S. Medan,Gen Watanabe,Gen Watanabe,Zhanguan Shi,Hisahi Kishi,Koji Y. Arai,Kazuyoshi Taya,Kazuyoshi Taya +9 more
TL;DR: Results indicate that immunoneutralization of endogenous inhibin is a new practical alternative for induction of superovulation as a substitution for eCG-hCG method in the adult rat.
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Tumor Necrosis Factor α (TNF) Increases Granulosa Cell Proliferation: Dependence on c-Jun and TNF Receptor Type 1
TL;DR: It is demonstrated that TNF increased c-Jun by activating stress-activated protein kinase/c-Jun-NH(2)-teminal kinase signaling via TNFR1 in mouse granulosa cells, and the induced c- Jun resulted in increased cell proliferation.