K
Kondapalli Venkata Gowri Chandra Sekhar
Researcher at Birla Institute of Technology and Science
Publications - 62
Citations - 891
Kondapalli Venkata Gowri Chandra Sekhar is an academic researcher from Birla Institute of Technology and Science. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 13, co-authored 50 publications receiving 496 citations.
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Journal ArticleDOI
Oxindole and its derivatives: A review on recent progress in biological activities.
Yogesh Mahadu Khetmalis,Mithula Shivani,Sankaranarayanan Murugesan,Kondapalli Venkata Gowri Chandra Sekhar +3 more
TL;DR: In this paper, the authors provide a description of the general chemistry based on existing corresponding structureactivity relationships (SARs) and compile all recent developmentary studies on oxindole-derived compounds as a successful pharmaceutical agent.
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Druggable targets of SARS-CoV-2 and treatment opportunities for COVID-19
Faheem,Banoth Karan Kumar,Kondapalli Venkata Gowri Chandra Sekhar,Selvaraj Kunjiappan,Joazaizulfazli Jamalis,Rafael Balaña-Fouce,Babu L. Tekwani,Murugesan Sankaranarayanan +7 more
TL;DR: This review presents a critical analysis of druggable targets of SARS CoV-2, new drug discovery, development, and treatment opportunities for COVID-19, and repurposing of existing drugs that were found to be effective against other RNA viruses.
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Seeking potent anti-tubercular agents: Design, synthesis, anti-tubercular activity and docking study of various ((triazoles/indole)-piperazin-1-yl/1,4-diazepan-1-yl)benzo[d]isoxazole derivatives.
Kalaga Mahalakshmi Naidu,Singireddi Srinivasarao,Napiórkowska Agnieszka,Augustynowicz-Kopeć Ewa,Muthyala Murali Krishna Kumar,Kondapalli Venkata Gowri Chandra Sekhar +5 more
TL;DR: 7i, 7j, 7y and 7z were found to be non-toxic against mouse macrophage cell lines when screened for toxicity and in vitro anti-tubercular activity against Mycobacterium tuberculosis H37Rv strain and two 'wild' strains.
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An expeditious synthesis of 1-aryl-4-methyl-1,2,4-triazolo[4,3-a]quinoxalines under solvent-free conditions using iodobenzene diacetate
Dalip Kumar,Kondapalli Venkata Gowri Chandra Sekhar,Harmeet Dhillon,V. S. Rao,Rajender S. Varma +4 more
TL;DR: A solvent-free and expeditious synthesis of 1-aryl-4-methyl-1,2,4-triazolo[4,3-a]quinoxalines is described in this paper.
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Design, synthesis and evaluation of 6-(4-((substituted-1H-1,2,3-triazol-4-yl)methyl)piperazin-1-yl)phenanthridine analogues as antimycobacterial agents.
Hunsur Nagendra Nagesh,Kalaga Mahalakshmi Naidu,Damarla Harika Rao,Jonnalagadda Padma Sridevi,Dharmarajan Sriram,Perumal Yogeeswari,Kondapalli Venkata Gowri Chandra Sekhar +6 more
TL;DR: Focus in this Letter is made to design and synthesize a series of nineteen new 6-(4-((substituted-1H-1,2,3-triazol-4-yl)methyl)phenanthridine analogues employing click chemistry and evaluated for their anti-tubercular activity against Mycobacterium tuberculosis H37Rv.