K
Konrad Siala
Researcher at Charles University in Prague
Publications - 22
Citations - 524
Konrad Siala is an academic researcher from Charles University in Prague. The author has contributed to research in topics: DNA repair & Ulcerative colitis. The author has an hindex of 9, co-authored 22 publications receiving 502 citations.
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Journal ArticleDOI
Effects of a Specially Designed Fermented Milk Product Containing Probiotic Lactobacillus casei DN-114 001 and the Eradication of H. pylori in Children: A Prospective Randomized Double-Blind Study
Josef Sýkora,Kristýna Valecková,Jana Amlerová,Konrad Siala,Petr Dedek,Stephen Watkins,J. Varvarovska,Frantisek Stozický,Petr Pazdiora,Jan Schwarz +9 more
TL;DR: In this paper, the efficacy of triple therapy supplemented with a specially designed fermented milk product containing specific probiotic Lactobacillus casei (L casei) DN-114 001 strain on Helicobacter pylori eradication in children was evaluated.
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Aspects of oxidative stress in children with Type 1 diabetes mellitus
Jana Varvařovská,Jaroslav Racek,Rudolf Štětina,Josef Sýkora,Renata Pomahačová,Zdeněk Rušavý,Silvie Lacigová,Ladislav Trefil,Konrad Siala,František Stožický +9 more
TL;DR: In this article, the level of DNA strand breaks as well as DNA repair processes using comet assay modifications was examined in children with Type 1 diabetes and their 1st degree relatives and confirmed increased oxidative stress in diabetic children.
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Epidemiology of Helicobacter pylori Infection in Asymptomatic Children: A Prospective Population-Based Study from the Czech Republic. Application of a Monoclonal-Based Antigen-in-Stool Enzyme Immunoassay
TL;DR: Evaluation of the prevalence of H. pylori infection in a population‐based sample of asymptomatic children in the Czech Republic to identify potential risk factors associated with this infection.
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Cytokine Tumor Necrosis Factor-alpha A Promoter Gene Polymorphism at Position −308 G→a and Pediatric Inflammatory Bowel Disease: Implications in Ulcerative Colitis and Crohn's Disease
Josef Sýkora,Subrt I,Dìdek P,Konrad Siala,Jan Schwarz,Machalová,J. Varvarovska,Petr Pazdiora,Pozler O,Frantisek Stozický +9 more
TL;DR: Although not necessarily dictating IBD initiation, the TNF-&agr; 308 A polymorphism may play a role in modifying the CD phenotype and may influence disease activity as well as more intense inflammatory activity in both forms of IBD and may modify the progression of chronic digestive tract inflammation.
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Evaluation of faecal calprotectin as a valuable non-invasive marker in distinguishing gut pathogens in young children with acute gastroenteritis.
TL;DR: Evaluation of faecal calprotectin in children ≤3 years of age with acute gastroenteritis with AG as an early predictor of bacterial inflammation shows promising results.