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Kouhei Kitagawa

Researcher at Okayama University

Publications -  9
Citations -  156

Kouhei Kitagawa is an academic researcher from Okayama University. The author has contributed to research in topics: Adrenocorticotropic hormone & Imipramine. The author has an hindex of 8, co-authored 9 publications receiving 148 citations.

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Effects of bupropion on the forced swim test and release of dopamine in the nucleus accumbens in ACTH-treated rats.

TL;DR: The findings suggest the antidepressant-like effect of bupropion to be related to levels of dopamine in the rat nucleus accumbens, specifically in relation to the site of action through the use of microinjections into the medial prefrontal cortex and nucleus Accumbens.
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Effects of imipramine and bupropion on the duration of immobility of ACTH-treated rats in the forced swim test: involvement of the expression of 5-HT2A receptor mRNA.

TL;DR: It is suggested that bupropion has the effect of reducing immobility time in the forced swim test in the tricyclic antidepressant-resistant depressive model induced by chronic ACTH treatment in rats, and that decreased 5-HT(2A) receptor mRNA levels may be involved in this phenomenon.
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Effects of pramipexole on the duration of immobility during the forced swim test in normal and ACTH-treated rats.

TL;DR: The results of these experiments suggested that pramipexole, administered into the intranucleus accumbens rather than the medial prefrontal cortex, exerted an antidepressant-like effect on ACTH-treated rats via the dopaminergic system.
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Chronic coadministration of carbamazepine together with imipramine produces antidepressant-like effects in an ACTH-induced animal model of treatment-resistant depression: involvement of 5-HT(2A) receptors?

TL;DR: The results suggest that the use of carbamazepine together with tricyclic antidepressants had the effect of reducing immobility time in the FST in a tricycleclic antidepressant-treatment-resistant depressive model induced by chronic ACTH treatment.
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The 5-HT1A receptor full agonist, 8-OH-DPAT inhibits ACTH-induced 5-HT2A receptor hyperfunction in rats: involvement of 5-HT1A receptors in the DOI-induced wet-dog shakes in ACTH-treated rats.

TL;DR: It is suggested that chronic treatment with ACTH decreased the5-HT1A receptor system; however, the inhibitory effects from the 5- HT1A receptors to the 4-HT2A receptors is not inhibited in ACTH-treated rats.