K
Krzysztof Marycz
Researcher at International Institute of Minnesota
Publications - 229
Citations - 4302
Krzysztof Marycz is an academic researcher from International Institute of Minnesota. The author has contributed to research in topics: Mesenchymal stem cell & Stem cell. The author has an hindex of 30, co-authored 197 publications receiving 3121 citations. Previous affiliations of Krzysztof Marycz include University of Giessen & Wroclaw University of Environmental and Life Sciences.
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Journal ArticleDOI
The Influence of Aging on the Regenerative Potential of Human Adipose Derived Mesenchymal Stem Cells
Monika Marędziak,Krzysztof Marycz,Krzysztof A. Tomaszewski,Katarzyna Kornicka,Brandon Michael Henry +4 more
TL;DR: Compared to younger cells, aged hASCs had decreased proliferation rates, decreased chondrogenic and osteogenic potential, and increased senescent features, and a shift in favor of adipogenic differentiation with increased age was observed.
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Study on Alginate⁻Chitosan Complex Formed with Different Polymers Ratio.
TL;DR: Results of this study showed that thermal decomposition temperature depends on the polymer ratio (R) and thermal resistance of samples was improved by increasing chitosan dosage, and polyelectrolyte complexation led to obtain more flexible and resistant to mechanical deformation materials.
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Dysfunction of Mesenchymal Stem Cells Isolated from Metabolic Syndrome and Type 2 Diabetic Patients as Result of Oxidative Stress and Autophagy may Limit Their Potential Therapeutic Use.
TL;DR: This review has focused on how type 2 diabetes and metabolic syndrome affect MSC properties, and thus limit their therapeutic potential, and mainly focuses on apoptosis, autophagy and mitochondria deterioration processes that indirectly affects MSC fate.
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The Effect of Age on Osteogenic and Adipogenic Differentiation Potential of Human Adipose Derived Stromal Stem Cells (hASCs) and the Impact of Stress Factors in the Course of the Differentiation Process.
Katarzyna Kornicka,Krzysztof Marycz,Krzysztof A. Tomaszewski,Monika Marędziak,Agnieszka Śmieszek +4 more
TL;DR: The results suggest that due to aging some cellular modification may be required before applying aged cells efficiently in therapies such as tissue engineering and regenerative medicine.
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Equine Metabolic Syndrome Affects Viability, Senescence, and Stress Factors of Equine Adipose-Derived Mesenchymal Stromal Stem Cells: New Insight into EqASCs Isolated from EMS Horses in the Context of Their Aging
TL;DR: The results suggest that the toxic compounds, accumulating in the mitochondria under oxidative stress, lead to alternations in their morphology and may be partially responsible for the senescent phenotype and decreased proliferation potential of ASCEMS.