K
Kuan-Teh Jeang
Researcher at Laboratory of Molecular Biology
Publications - 1
Citations - 483
Kuan-Teh Jeang is an academic researcher from Laboratory of Molecular Biology. The author has contributed to research in topics: Protease & Saquinavir. The author has an hindex of 1, co-authored 1 publications receiving 476 citations.
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HIV-1 protease inhibitors are substrates for the MDR1 multidrug transporter.
Caroline G.L. Lee,Michael M. Gottesman,Carol O. Cardarelli,Murali Ramachandra,Kuan-Teh Jeang,Suresh V. Ambudkar,Ira Pastan,Saibal Dey +7 more
TL;DR: It is indicated that cells in patients that express the MDR1 transporter will be relatively resistant to the anti-viral effects of the HIV-1 protease inhibitors, and that absorption, excretion, and distribution of these inhibitors in the body may be affected by the multidrug transporter.