Molecular imprinting technology (MIT), often described as a method of making a molecular lock to match a molecular key, is a technique for the creation of molecularly imprinted polymers (MIPs) with tailor-made binding sites complementary to the template molecules in shape, size and functional groups. Owing to their unique features of structure predictability, recognition specificity and application universality, MIPs have found a wide range of applications in various fields. Herein, we propose to comprehensively review the recent advances in molecular imprinting including versatile perspectives and applications, concerning novel preparation technologies and strategies of MIT, and highlight the applications of MIPs. The fundamentals of MIPs involving essential elements, preparation procedures and characterization methods are briefly outlined. Smart MIT for MIPs is especially highlighted including ingenious MIT (surface imprinting, nanoimprinting, etc.), special strategies of MIT (dummy imprinting, segment imprinting, etc.) and stimuli-responsive MIT (single/dual/multi-responsive technology). By virtue of smart MIT, new formatted MIPs gain popularity for versatile applications, including sample pretreatment/chromatographic separation (solid phase extraction, monolithic column chromatography, etc.) and chemical/biological sensing (electrochemical sensing, fluorescence sensing, etc.). Finally, we propose the remaining challenges and future perspectives to accelerate the development of MIT, and to utilize it for further developing versatile MIPs with a wide range of applications (650 references).

http://ir.yic.ac.cn/bitstream/133337/17045/1/Molecular%20imprinting%20perspectives%20and%20applications.pdf

Molecular imprinting: perspectives and applications

Herein, we present a survey of the literature covering the development of molecular imprinting science and technology over the years 2004-2011. In total, 3779 references to the original papers, rev ...

Molecular imprinting science and technology: a survey of the literature for the years 2004-2011.

Dispersive solid-phase extraction (dSPE) is a sorbent-based technique widely applied in sample preparation for both sample clean up or analite preconcentration. It shows considerable benefits over conventional SPE, especially in terms of the simplicity of the procedure. This chapter aims at providing a general overview of dSPE, its different extraction approaches (dSPE, µ-dSPE and magnetic-dSPE), and the principal factors which influence the extraction process (including the sorbents most frequently used) as well as its most common applications.



Keywords:

dispersive solid-phase extraction;
liquid-liquid extraction;
QuEChERS method;
sorbent-based technique

Dispersive Solid‐Phase Extraction

Magnetic separation techniques in sample preparation for biological analysis: a review.

Molecularly imprinted polymers are synthetic polymers possessing specific cavities designed for target molecules. They are prepared by copolymerization of a cross-linking agent with the complex formed from a template and monomers that have functional groups specifically interacting with the template through covalent or noncovalent bonds. Subsequent removal of the imprint template leaves specific cavities whose shape, size, and functional groups are complementary to the template molecule. Because of their predetermined selectivity, molecularly imprinted polymers (MIPs) can be used as ideal materials in wastewater treatment. Especially, MIP-based composites offer a wide range of potentialities in wastewater treatment. This paper reviews the latest applications of MIPs in wastewater treatment, highlights the development of MIP-based composites in wastewater, and offers suggestions for future success in the field of MIPs.

Application of molecularly imprinted polymers in wastewater treatment: a review.

Self-assembly molecularly imprinted polymers of 17β-estradiol on the surface of magnetic nanoparticles for selective separation and detection of estrogenic hormones in feeds

Kunfang Ma

Papers

Self-assembly molecularly imprinted polymers of 17β-estradiol on the surface of magnetic nanoparticles for selective separation and detection of estrogenic hormones in feeds

Preparation of estriol–molecularly imprinted silica nanoparticles for determining oestrogens in milk tablets