K
Kunhard Pollow
Researcher at Free University of Berlin
Publications - 39
Citations - 589
Kunhard Pollow is an academic researcher from Free University of Berlin. The author has contributed to research in topics: Microsome & Estrone. The author has an hindex of 11, co-authored 39 publications receiving 583 citations.
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Journal ArticleDOI
Conception and pharmacodynamic profile of drospirenone.
Walter Elger,Sybille Beier,Kunhard Pollow,Robert E. Garfield,Shao Qing Shi,Alexander Hillisch +5 more
TL;DR: DRSP prevented the mild increase of blood pressure seen under a conventional levonorgestrel-containing contraceptive and even tended to reduce pretreatment blood pressure, and powerful antiandrogenic effects were seen in gonad intact and testosterone substituted castrated male rats.
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Characterization and Comparison of Receptors for 17β-Estradiol and Progesterone in Human Proliferative Endometrium and Endometrial Carcinoma
TL;DR: Elution profiles from agarose gel and ion exchange columns, as well as electrophoretic patterns from isoelectric focusing, revealed a similarity between biochemical properties of the receptors from endometrial carcinoma and proliferative endometrium.
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Comparison of the in vitro conversion of estradiol-17 beta to estrone of normal and neoplastic human breast tissue.
TL;DR: Kinetic parameters (Km-values, coenzyme requirements and maximal velocities) of a cytoplasmic, nuclear, mitochondrial and microsomal 17 beta-HSD of normal and neoplastic human mammary tissue were compared and Sulphydryl groups were shown to be essential for catalysis.
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Determination of Estradiol, Estrone, and Progesterone in Serum and Myometrium: Correlation with the Content of Sex Steroid Receptors and 17β-Hydroxysteroid Dehydrogenase Activity throughout the Menstrual Cycle
TL;DR: The midcycle peak of the cytoplasmic progester one-binding capacity and the increase of progesterone tissue levels at the same time were followed by an acti...
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Progesterone Metabolism in Normal Human Endometrium During the Menstrual Cycle and in Endometrial Carcinoma
TL;DR: Different subcellular fractions (purity checked by electron microscopy and respective marker enzymes) were incubated with 0.1 muCi 14C-progesterone, indicating the presence of a 20alpha-hydroxysteroid dehydrogenase (20alpha-HSD) and 5alpha- and 5beta-reductases, and Kinetic parameters (Km-values, coenzyme requirements and maximum velocities) were determined.