Kunikazu Tanji

TL;DR: The histopathological findings suggest that the neuronal cell death observed in the thalamus in hydrocephalic HTX rats is retrograde degeneration due to extensive damage of axons in the cerebral white matter and that theThalamic retrogrades degeneration is attributable to apoptotic cell death.

TL;DR: Investigation of the cranial and spinal nerves and dorsal root ganglia of patients with LBD indicates that α‐synuclein pathology in the peripheral nerves is axonal‐predominant in LBD, whereas it is restricted to glial cells in MSA.

TL;DR: In the brain of patients with PD and DLB, NUB1 accumulates in the presynapses in the hippocampus, cerebral neocortex, and substantia nigra in which PK-resistant &agr;-synuclein is deposited.

TL;DR: The presence of FOXO1, SESN3 and TSC2 in brainstem-type LBs is demonstrated for the first time and suggests that autophagy modulators are incorporated into LBs and that the expression of these proteins can be increased by various factors including aging.

TL;DR: It is demonstrated that IFN-gamma stimulates endometrial epithelial cells to produce CXCL11, which is implicated in implantation and pregnancy and RNA interference against RIG-I resulted in the suppression of the IFN -gamma-induced CXCl11 expression.