Hidemi Yoshida

TL;DR: It is shown that inherited deficiency of PAF acetylhydrolase is the result of a point mutation in exon 9 and that this mutation completely abolishes enzymatic activity.

TL;DR: Fractalkine plays an important role in the interaction between leukocytes and endothelial cells and is inhibited by the soluble form of IL-6 receptor-alpha, 15-deoxy-Delta(12,14)-prostaglandin J(2), and hypoxia.

TL;DR: IFN‐γ‐induced production of galectin‐9 by endothelial cells may play an important role in immune responses by regulating interactions between the vascular wall and eosinophils.

TL;DR: Plasma PAF acetylhydrolase deficiency may be a risk factor for stroke, and may explain the relatively high prevalence of stroke in Japan, as the mutation is more common among Japanese than Caucasians.

TL;DR: Retinoic acid-inducible gene I (RIG-I) is found to be an inducible gene in stimulated endothelial cells that may have important roles in vascular pathology by virtue of its ability to regulate expression of the COX-2 gene product.