Kyu Sang Lee

TL;DR: It is demonstrated that higher densities of both intratumoral CD8+ and FoxP3+ TILs are associated with good prognosis, suggesting a synergistic activity of these 2 subsets that can be used as an independent prognostic factor in MSI-high GCs.

TL;DR: This study confirmed that EMT is an intrinsic characteristic of basal-like subtype and is associated with CSC phenotype and showed higher expression of EMT markers in invasive carcinomas than in pure DCIS, especially in basal- like subtype, and in the invasive component of basal -like breast cancers, suggesting that E MT may be involved in the progression from in situ to invasive basal-Like breast cancers.

TL;DR: CD274 expression in tumor-infiltrating immune cells was an independent factor for improved prognosis in CRC patients and a deeper understanding of CD274 status may yield improved responses to future CRC immunotherapies.

TL;DR: Increase in tumor PD-L1 expression may predict poor clinical outcome after platinum-based NACT, and that pattern was consistent across clinically defined subgroups except for patients with partial response to NACT.

TL;DR: In this article, the authors determined the incidence and clinicopathological significance of c-MYC gene copy-number (GCN) gain in patients with primary colorectal cancer (CRC).