K
Kyun-Seop Bae
Researcher at Asan Medical Center
Publications - 123
Citations - 1555
Kyun-Seop Bae is an academic researcher from Asan Medical Center. The author has contributed to research in topics: Pharmacokinetics & Tolerability. The author has an hindex of 19, co-authored 116 publications receiving 1313 citations. Previous affiliations of Kyun-Seop Bae include University of Ulsan & New Generation University College.
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Journal ArticleDOI
Pharmacokinetics of Hydroxychloroquine and Its Clinical Implications in Chemoprophylaxis against Malaria Caused by Plasmodium vivax
Hyeong-Seok Lim,Jeong-Soo Im,Joo Youn Cho,Kyun-Seop Bae,Terry A. Klein,Joon Sup Yeom,Tae-Seon Kim,Jae-Seon Choi,In-Jin Jang,Jae-Won Park +9 more
TL;DR: Hydroxychloroquine is an antimalarial drug used as chemoprophylaxis against malaria caused by Plasmodium vivax in the Republic of Korea Army (ROKA), and a significant cause of prophylactic failure among the individuals in ROKA was ascribed to plasma concentrations of HCQ lower than those predicted by the PK model.
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Effect of omeprazole on the pharmacokinetics of moclobemide according to the genetic polymorphism of CYP2C19.
Kyung-Sang Yu,Kyung-Sang Yu,Dong-Seok Yim,Dong-Seok Yim,Joo Youn Cho,Joo Youn Cho,Soon Seong Park,Soon Seong Park,Ji Young Park,Ji Young Park,Kyunghoon Lee,Kyunghoon Lee,In-Jin Jang,In-Jin Jang,So-Young Yi,So-Young Yi,Kyun-Seop Bae,Kyun-Seop Bae,Sang-Goo Shin,Sang-Goo Shin +19 more
TL;DR: Moclobemide, an antidepressant with selective monoamine oxidase‐A inhibitory action, is known to be metabolized by CYP2C19 and is also reported to be an inhibitor of CYP 2C19, CYP3A2, and CYP1A2.
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Pharmacokinetics and pharmacodynamics of propofol microemulsion and lipid emulsion after an intravenous bolus and variable rate infusion.
Kye Min Kim,Byung Moon Choi,Si Won Park,Soo Han Lee,Lane V. Christensen,Jiaye Zhou,Byung Hoon Yoo,Hye Won Shin,Kyun-Seop Bae,Steven E. Kern,Sung Hong Kang,Gyu-Jeong Noh +11 more
TL;DR: The efficacy and safety of Aquafol were not different from those of Diprivan® within the dose range in this study, and the population pharmacokinetics and pharmacodynamics revealed a variety of differences between two formulations.
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Pharmacokinetic and Pharmacodynamic Evaluation of a Novel Proton Pump Inhibitor, YH1885, in Healthy Volunteers
Kyung-Sang Yu,Kyun-Seop Bae,Ji-Hong Shon,Joo Youn Cho,So-Young Yi,Jae Yong Chung,Hyeong-Seok Lim,In-Jin Jang,In-Jin Jang,Sang-Goo Shin,Sang-Goo Shin,Keun-Seog Song,Byoung-Seok Moon +12 more
TL;DR: YH1885 was found to be safe and well tolerated and effectively inhibited acid secretion with dose‐dependent increases in intragastric pH and acid‐suppressing efficacy needs to be further evaluated in patients with gastric acid‐related diseases.
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The thickness and texture of temporal bone in brain CT predict acoustic window failure of transcranial Doppler.
TL;DR: This study reveals whether initial brain CT of acute stroke patients predicted TAWF, and transcranial Doppler is useful for evaluation and treatment of ischemic stroke.