L
L C Hoskins
Researcher at Bristol Royal Infirmary
Publications - 1
Citations - 262
L C Hoskins is an academic researcher from Bristol Royal Infirmary. The author has contributed to research in topics: Mucin & N-acetylneuraminate lyase. The author has an hindex of 1, co-authored 1 publications receiving 246 citations.
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Mucin degradation in the human colon: production of sialidase, sialate O-acetylesterase, N-acetylneuraminate lyase, arylesterase, and glycosulfatase activities by strains of fecal bacteria.
TL;DR: It is concluded that the presence of two or more O-acetyl groups on sialic acids inhibits enteric bacterial sialidases but that production of sialate O-acetylesterases by several populations of enteric bacteria lessens the likelihood that mucin oligosaccharide chains terminating in O- acetylated sIALic acids are protected from degradation.