L
Lambert Brandsma
Researcher at Utrecht University
Publications - 461
Citations - 6491
Lambert Brandsma is an academic researcher from Utrecht University. The author has contributed to research in topics: Alkyl & Catalysis. The author has an hindex of 33, co-authored 461 publications receiving 6394 citations. Previous affiliations of Lambert Brandsma include Russian Academy.
Papers
More filters
Journal ArticleDOI
Structure and serotonin 5-HT2c receptor activity of ortho- and meta-substituted phenylpiperazines
M.L. Verdonk,J. W. Voogd,Jan A. Kanters,Jan M. Kroon,R. den Besten,Lambert Brandsma,D. Leysen,Jan Kelder +7 more
TL;DR: The hypothesis that the conformation for which the piperazine ring and the phenyl ring are approximately co-planar should be the 5-HT2C receptor 'activating' conformation is used to predict the activities of the two novel 5- HT2C ligands oMPP and mMPP.
Journal ArticleDOI
Reaction of lithioalkoxyallenes with isothio-cyanates: Synthesis of pyrroles and 5,6-dihydropyridines
TL;DR: In this paper, a novel synthesis route for 2,3-disubstituted pyrroles and 5,6-dihydropyridines, starting from lithiated alkoxyallenes, and organic isothiocyanates, was proposed.
Journal ArticleDOI
New synthesis of quinolines from lithiated allenes and isothiocyanates
TL;DR: In this article, a new route for the synthesis of quinolines based on the reaction of lithiated allenes with phenyl isothiocyanate was proposed.
Journal ArticleDOI
Synthesis of 5-alkoxy-2-alkylthio-3-pyrrol-2-ylpyrroles
Journal ArticleDOI
Dramatic acceleration of alkylation reactions with organolithium compounds by potassium tert-butoxide.
TL;DR: In this paper, the reaction of organolithium compounds with alkyl halides and with epoxides was accelerated by adding equivalent amounts of potassium tert-butoxide, and the reaction was shown to be reversible.