Laura J. Knoll

TL;DR: RNA-seq is a valuable tool to simultaneously analyze host and microbe transcriptomes and shows that T. gondii is metabolically active and synthesizing proteins at 28 days post-infection and that a distinct subset of host genes associated with the immune response are more abundant specifically during chronic infection.

TL;DR: In this paper, the authors employed caged major histocompatibility complex molecules to generate ∼ 250 H-2L d tetramers and to distinguish T. gondii-specific CD8 + T cells in BALB/c mice.

TL;DR: The authors' results shed light on the identity and the parasite stage-specificity of 2 CD8+ T cell epitopes recognized in the acute and chronic phase of infection with T. gondii.

TL;DR: An overview of what is known and unknown about the complex relationship between the host and parasite during the progression of T. gondii infection is provided, with the ultimate goal of bridging these events.

TL;DR: Findings suggest that while Toxoplasma and Plasmodium share similar HT/PEXEL motifs, Txoplasma HT/ PEXEL containing proteins interact with but do not cross the PVM.