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Leah R. Hanson

Researcher at HealthPartners

Publications -  107
Citations -  4930

Leah R. Hanson is an academic researcher from HealthPartners. The author has contributed to research in topics: Neuroprotection & Central nervous system. The author has an hindex of 29, co-authored 103 publications receiving 4148 citations. Previous affiliations of Leah R. Hanson include Regions Hospital & Henry M. Jackson Foundation for the Advancement of Military Medicine.

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Intranasal delivery to the central nervous system: Mechanisms and experimental considerations

TL;DR: This review focuses on the current understanding of the mechanisms underlying intranasal delivery to the central nervous system involving the olfactory and trigeminal nerves, the vasculature, the cerebrospinal fluid, and the lymphatic system.
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Intranasal delivery bypasses the blood-brain barrier to target therapeutic agents to the central nervous system and treat neurodegenerative disease

TL;DR: Intranasal delivery provides a practical, non-invasive method of bypassing the blood-brain barrier to deliver therapeutic agents to the brain and spinal cord, and can revolutionize the treatment of Alzheimer's disease, stroke, and other brain disorders.
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Intranasal administration of interferon beta bypasses the blood-brain barrier to target the central nervous system and cervical lymph nodes: a non-invasive treatment strategy for multiple sclerosis.

TL;DR: Intranasal administration offers a non-invasive method of drug delivery for multiple sclerosis (MS) that bypasses the blood-brain barrier (BBB) and directly targets the CNS and lymph nodes.
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DELIVERY OF INTERFERON-β TO THE MONKEY NERVOUS SYSTEM FOLLOWING INTRANASAL ADMINISTRATION

TL;DR: The results suggest intranasally applied macromolecules may bypass the blood-brain barrier and rapidly enter the primate CNS along olfactory- and trigeminal-associated extracellular pathways, as shown previously in the rat.
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Mindfulness-based stress reduction for family caregivers: a randomized controlled trial.

TL;DR: MBSR could reduce stress and improve mental health in caregivers of family members with dementia residing in the community and was more effective at improving overall mental health, reducing stress, and decreasing depression than CCES.