Showing papers by "Leelavinothan Pari published in 1998"
TL;DR: The study shows that Jamun seed extract (JSEt) has hypoglycaemic action and the decrease in thiobarbituric acid reactive substances (TBARS) and increase in reduced glutathione (GSH), superoxide dismutase (SOD) and catalase (CAT) clearly show the antioxidant property of the JSEt.
250 citations
TL;DR: It is revealed that carrot could afford a significant protective effect against lindane‐induced hepatotoxicity and restored the depressed antioxidants and HDL‐cholesterol levels to near normal.
Abstract: Daucus carota commonly known as carrot, is widely used in European folk medicine for the treatment of jaundice and hepatic disorders. Oral administration of carrot extract (25 mL/kg/day) for 30 days produced significant hepatoprotection against lindane (20 mg/kg/day) induced hepatotoxicity in rats. The increased levels of serum enzymes namely aspartate transaminase, alanine transaminase, alkaline phosphatase and the levels of thiobarbituric acid reactive substances, cholesterol, triglycerides and LDL-cholesterol in lindane administered rats were observed to be decreased significantly in the lindane + carrot extract group. The carrot extract also restored the depressed antioxidants and HDL-cholesterol levels to near normal. The results of this study reveal that carrot could afford a significant protective effect against lindane-induced hepatotoxicity. © 1998 John Wiley & Sons, Ltd.
19 citations
TL;DR: The results of this study revealed that Livex could afford significant protection against erythromycin estolate induced lipid peroxidation and produced enhancement of cellular antioxidant defence, revealing that the antioxidative action of Livex is responsible for its protective activity.
Abstract: The present study was carried out to investigate the antiperoxidative effect of Livex, a compound herbal formulation, against erythromycin estolate induced lipid peroxidation. The oral administration of Livex to rats along with erythromycin estolate caused a significant reversal in lipid peroxidation, enzymatic leakage and produced enhancement of cellular antioxidant defence, revealing that the antioxidative action of Livex is responsible for its protective activity. These observations were supplemented by histopathological examination of liver and kidney sections. The results of this study revealed that Livex could afford significant protection against erythromycin estolate induced lipid peroxidation.
18 citations