Showing papers by "Lei Zhang published in 1996"

Endoscopic ultrasonography assessment in preoperative staging for carcinoma of ampulla of Vater and extrahepatic bile duct.

Abstract: Objective To evaluate preoperatively the extent of primary tumor, involvement of regional lymph node, and distant metastasis of ampullary carcinoma and extra hepatic bile duct carcinoma. Methods 28 patients with ampullary carcinoma and the 18 patients with extrahepatic bile duct carcinoma were subjected to endoscopic ultrasonography (EUS). The results were compared with those of surgical explorations and pathological findings of the resected specimens for evaluating the accuracy of preoperative staging of EUS. 46 patients underwent surgical explorations. Radical resection with detailed pathological study was done for 22 patients with resectable ampullary carcinoma and 18 patients with extrahepatic bile duct carcinoma. Carcinomas of ampulla of Vater and extrahepatic bile duct were staged according to the tumor, nodes, metastasis (TNM) classification. Results The accurate rate of EUS in assessing the extent of cancer invasion was 81.8% for ampullary carcinoma, and 72.2% for extrahepatic bile duct carcinoma. The accuracy of EUS in predicting regional lymph node metastasis was 59% for ampullary carcinoma, and 61.1% for extrahepatic bile duct carcinoma. Invasion of portal vein was correctly predicted by EUS in 2 of 3 patients, but the 3 cases of liver metastasis were not detected by EUS. Conclusions EUS is an effective method for the evaluation of the extent of invasion of ampullary carcinoma and extrahepatic bile duct carcinoma as well as the involvement of regional lymph node before operation. Because of its limited penetration depth, however, EUS is inadequate in the assessment of liver metastasis.

[Anorectal malignant melanoma: report of 33 cases].

Abstract: 33 Cases of anorectal malignant melanoma (ARMM) diagnosed pathologically were treated in Tianjin Cancer Hospital from 1996 to 1994. Some of these patients were treated with abdominoperineal resection (Mile's operation) and local resection plus chemotherapy, biotherapy and radiotherapy, others were given chemotherapy only. 25 cases were followed up from six months up to six years. The results showed that the median survival time was 23.5 months in the group of Mile's, 17.5 months of local resection and 5.5 months in chemotherapy alone respectively. The authors considered that early diagnosis and treatment are the key to raise the survival rate. For the cases diagnosed pathologically the Mile's operation should be performed and groin dissection is necessary for cases of groin lymphatic metastasis.