Showing papers by "Lei Zhang published in 2004"
TL;DR: In this article, a dual-core photonic crystal fiber (DCPCF) consisting of pure silica and air is proposed, and the dispersion of this DCPCF can reach -18 000 ps/(nm/spl middot/km).
Abstract: A novel design of dual-core photonic crystal fiber (DCPCF) consisting of pure silica and air is proposed in this letter. In addition to potential low loss, simulation shows that dispersion of this DCPCF can reach -18 000 ps/(nm/spl middot/km).
128 citations
TL;DR: Passive antibody treatment of macaques prior to simian/human immunodeficiency virus infection produces “sterilizing immunity” in some animals and long-term reductions in viral loads in others.
Abstract: Passive antibody treatment of macaques prior to simian/human immunodeficiency virus infection produces “sterilizing immunity” in some animals and long-term reductions in viral loads in others. Analysis of viral kinetics suggests that antibody mediates sterilizing immunity by its effects on the initial viral inoculum. By contrast, reduction in peak viral load later in infection prevents CD4 depletion and contributes to long-term viral control.
24 citations
Journal Article•
TL;DR: There were significant relations between tobacco smoking and p53 alteration while there were no significant Relations between alcohol drinking and p 53 alteration.
Abstract: Objective To investigate the relationship between tobacco smoking,drinking and p53 alteration in esophageal carcinoma. Methods Literature on the relationship between p53 alteration in esophageal carcinoma and tobacco smoking,drinking through Meta-analysis were reviewed. Results In 14 selected papers related to tobacco smoking, pooled odds ratio (OR) of tobacco smoking with P53 overexpression and p53 alteration were 1.99(95% CI: 1.30-3.06) and 1.64(95% CI: 1.13-2.37), respectively (P 0.05). Pooled OR of tobacco smoking with p53 mutation was 1.11 (95% CI: 0.47-2.76) (P 0.05 ). In 11 selected papers on alcohol drinking, pooled OR of drinking with P53 overexpression,p53 mutation and p53 alteration were 1.30 (95 % CI : 0.83-2.04 ), 1.13 (95 % CI : 0.67-1.90) and 1.22(95% CI:0.87-1.72) respectively (P0.05). Conclusion There were significant relations between tobacco smoking and p53 alteration while there were no significant relations between alcohol drinking and p53 alteration.
7 citations
TL;DR: A novel all-solid Bragg fiber composed entirely of silica material is proposed, and simulations show that zero dispersion wavelength lambda0 near 1.55 m with nonlinear coefficient gamma about 50 W-1km-1 can be obtained in silica Bragg Fiber.
Abstract: A novel all-solid Bragg fiber composed entirely of silica material is proposed in this paper. The core of this Bragg fiber is composed of conventional silica, and the cladding is formed by a set of alternating layers of up-doped and down-doped silica. This all-solid silica Bragg fiber is technically feasible and can simplify the fabrication technique. Dispersion properties of this silica Bragg fiber are investigated, and simulations show that zero dispersion wavelength λ0 near 1.55 μm with nonlinear coefficient γ about 50 W-1km-1 can be obtained in silica Bragg fiber.
5 citations