https://cris.maastrichtuniversity.nl/ws/files/69061548/lambin_2012_radiomics_extracting_more_information.pdf

Radiomics: extracting more information from medical images using advanced feature analysis.

A review of NIR dyes in cancer targeting and imaging.

In vivo imaging, which enables us to peer deeply within living subjects, is producing tremendous opportunities both for clinical diagnostics and as a research tool. Contrast material is often required to clearly visualize the functional architecture of physiological structures. Recent advances in nanomaterials are becoming pivotal to generate the high-resolution, high-contrast images needed for accurate, precision diagnostics. Nanomaterials are playing major roles in imaging by delivering large imaging payloads, yielding improved sensitivity, multiplexing capacity, and modularity of design. Indeed, for several imaging modalities, nanomaterials are now not simply ancillary contrast entities, but are instead the original and sole source of image signal that make possible the modality’s existence. We address the physicochemical makeup/design of nanomaterials through the lens of the physical properties that produce contrast signal for the cognate imaging modality—we stratify nanomaterials on the basis of thei...

Nanomaterials for In Vivo Imaging

https://www.cell.com/trends/biotechnology/pdf/S0167-7799(11)00017-5.pdf

Photoacoustic imaging in cancer detection, diagnosis, and treatment guidance

OBJECTIVE. The objective of our study was to compare T2-weighted MRI alone and T2 combined with diffusion-weighted imaging (DWI) for the localization of prostate cancer.SUBJECTS AND METHODS. T2-weighted imaging and DWI (b value = 600 s/mm2) were performed in 49 patients before radical prostatectomy using an endorectal coil at 1.5 T in this prospective trial. The peripheral zone of the prostate was divided into sextants and the transition zone into left and right halves. T2 images alone and then T2 images combined with apparent diffusion coefficient (ADC) maps (T2 + DWI) were scored for the likelihood of tumor and were compared with whole-mount histology results. Fixed window and level settings were used to display the ADC maps. Only tumors with an area of more than 0.13 cm2 (> 4 mm diameter) and a Gleason score of ≥ 6 were considered significant. The area under the receiver operating characteristic curve (Az) was used to assess accuracy.RESULTS. In the peripheral zone, the Az value was significantly highe...

https://www.ajronline.org/doi/pdf/10.2214/AJR.07.2211

Combined T2-Weighted and Diffusion-Weighted MRI for Localization of Prostate Cancer

https://febs.onlinelibrary.wiley.com/doi/pdf/10.1016/j.molonc.2008.04.001

Leonard Fass

Papers

Imaging and cancer: A review