L
Leonidas Sakkas
Researcher at Aristotle University of Thessaloniki
Publications - 19
Citations - 457
Leonidas Sakkas is an academic researcher from Aristotle University of Thessaloniki. The author has contributed to research in topics: Lung cancer & Cancer. The author has an hindex of 12, co-authored 19 publications receiving 387 citations.
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Journal ArticleDOI
Extrapelvic endometriosis: a rare entity or an under diagnosed condition?
Nikolaos Machairiotis,Aikaterini Stylianaki,Georgios Dryllis,Paul Zarogoulidis,Paraskevi Kouroutou,Nikolaos Tsiamis,Nikolaos Katsikogiannis,Eirini Sarika,Nikolaos Courcoutsakis,Theodora Tsiouda,Andreas Gschwendtner,Konstantinos Zarogoulidis,Leonidas Sakkas,Aggeliki Baliaka,Christodoulos Machairiotis +14 more
TL;DR: The multipotent localization of endometriosis in combination with the wide range of its clinical expression should raise the clinical suspicion in every woman with periodic symptoms of extrapelvic organs.
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Solitary papillomas of the lower airways: epidemiological, clinical, and therapeutic data during a 22-year period and review of the literature.
Stavros Tryfon,Vasiliki Dramba,Fotis Zoglopitis,Dimitris Iakovidis,Leonidas Sakkas,Theodoros Kontakiotis,Nikolaos I. Galanis +6 more
TL;DR: The estimated incidence of solitary respiratory papillomas is 3.95 cases/100,000 patients/yr, and SRPs occur more commonly in men (ratio 3:1), and the distribution of mixed type papilloma is from the third to the sixth decade of life.
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Docetaxel-carboplatin in combination with erlotinib and/or bevacizumab in patients with non-small cell lung cancer
Eftimia Boutsikou,Theodoros Kontakiotis,Paul Zarogoulidis,Kaid Darwiche,Ellada Eleptheriadou,Konstantinos Porpodis,Grammati Galaktidou,Leonidas Sakkas,Wolfgang Hohenforst-Schmidt,Kosmas Tsakiridis,Theodoros Karaiskos,Konstantinos Zarogoulidis +11 more
TL;DR: Administration of bevacizumab and erlotinib in combination with first-line chemotherapy, followed by bevicizumAB and er Lotinib monotherapy as maintenance, showed promising results in patients with NSCLC, with reduced toxicity as compared with chemotherapy alone, but did not translate into longer overall survival.
Journal ArticleDOI
Pleura space anatomy.
Charalampos Charalampidis,Andrianna Youroukou,George Lazaridis,Sofia Baka,Ioannis Mpoukovinas,Vasilis Karavasilis,Ioannis Kioumis,Georgia Pitsiou,Antonis Papaiwannou,Anastasia Karavergou,Kosmas Tsakiridis,Nikolaos Katsikogiannis,Eirini Sarika,Konstantinos Kapanidis,Leonidas Sakkas,Ipokratis Korantzis,Sofia Lampaki,Konstantinos Zarogoulidis,Paul Zarogoulidis +18 more
TL;DR: The pleural cavity is the potential space between the two pleurae (visceral and parietal) of the lungs that is highly sensitive to pain, while the visceral pleura are not, due to its lack of sensory innervation.
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Interleukin-7 and interleukin-15 for cancer.
Paul Zarogoulidis,Sofia Lampaki,Lonny Yarmus,Ioannis Kioumis,Georgia Pitsiou,Nikolaos Katsikogiannis,Wolfgang Hohenforst-Schmidt,Qiang Li,Haidong Huang,Antonios Sakkas,John Organtzis,Leonidas Sakkas,Ioannis Mpoukovinas,Kosmas Tsakiridis,George Lazaridis,Konstantinos N. Syrigos,Konstantinos Zarogoulidis +16 more
TL;DR: Interleukin 7 and 15 are considered powerful pro-inflammatory cytokines, they have the ability to destabilize chromosomes and induce tumorigenesis, and can control malignancy proliferation by influencing the tumor microenvironment and immune system.